文献类型：期刊文献

英文题名：Transcriptome Analysis of Different Stages in the Early Ovarian Development of the Greater Amberjack (Seriola dumerili)

作者：Deng, Qiuxia[1];Huang, Yang[1,2];Ru, Xiaoying[2];Lin, Haoyi[1];You, Xinxin[1];Hao, Ruijuan[2];Li, Hang[2];Hu, Qin[2];Zhang, Dongying[2];Zhao, Yanfei[3];Wu, Jinhui[3];Li, Guangli[1];Zhu, Chunhua[1,2]

机构：[1]Guangdong Ocean Univ, Fisheries Coll, Guangdong Res Ctr Reprod Control & Breeding Techno, Guangdong Prov Key Lab Aquat Anim Dis Control & Hl, Zhanjiang 524088, Peoples R China;[2]Southern Marine Sci & Engn Guangdong Lab Zhanjiang, Dev & Res Ctr Biol Marine Resources, Zhanjiang 524025, Peoples R China;[3]Agrotech Extens Ctr Guangdong Prov, Guangzhou 510500, Peoples R China

年份：2026

卷号：16

期号：5

外文期刊名：ANIMALS

收录：SCI-EXPANDED(收录号：WOS:001713295400001)、、WOS

基金：This research was funded by the fund of Guangdong Ocean University (grant number 030301022301), the Southern Marine Science and Engineering Guangdong Laboratory (Zhanjiang) (grant number ZJW-2023-10), research on breeding technology of candidate species for Guangdong modern marine ranching (grant number 2024-MRB-00-001), and 2025 research on breeding technology of candidate species for Guangdong modern marine (2025-MRB-00-001).

语种：英文

外文关键词：Seriola dumerili; early ovarian development; transcriptome analysis; different stages; functional analysis

外文摘要：The greater amberjack (Seriola dumerili) is a globally important aquaculture fish species belonging to the family Carangidae. However, current research on the ovarian development and regulation of the greater amberjack is limited, particularly with regard to early ovarian development in artificially bred individuals. Therefore, this study aims to analyze the ovarian transcriptomes at the primary growth stage in one-year-old fish at the chromatin nucleolar stage and two-year-old fish at the perinucleolar stage to suggest how early ovarian development takes place in artificially bred greater amberjacks. To do this, the study constructed ovarian mRNA expression profiles of different stages of artificially bred fish and identified differentially expressed genes (DEGs), Gene Ontology terms, and Kyoto Encyclopedia of Genes and Genomes pathways important for various physiological processes. A functional analysis revealed that the DEGs closely related to ovarian development were involved in cell growth and death (e.g., ccnd1, cdk1, cdc6, cdc25b, fbxo43, cdkn1a and cdkn1d), the TGF-beta signaling pathway (e.g., gdf6, bmpr1b, gsdf, amh, tgfb3, and smad6), steroid hormone biosynthesis (e.g., hsd3b1, hsd11b2, hsd17b12 and hsd20b2), and the endocrine system (e.g., mapk8a, mapk11, mapk12a, mapk13 and adcy9). These findings suggest that ovarian development is the result of the coordinated regulation of various genes responsible for various functions. This study provides a theoretical basis for exploring the underlying molecular mechanisms of early ovarian development in artificially bred greater amberjacks.