文献类型：期刊文献

英文题名：Endocrine disrupting effects in western mosquitofish Gambusia affinis in two rivers impacted by untreated rural domestic wastewaters

作者：Huang, Guo-Yong[1,2];Liu, You-Sheng[1,2];Liang, Yan-Qiu[3];Shi, Wen-Jun[1,2];Yang, Yuan-Yuan[1,2];Liu, Shuang-Shuang[4];Hu, Li-Xin[1,2];Chen, Hong-Xing[1,2];Xie, Lingtian[1,2];Ying, Guang-Guo[1,2]

机构：[1]South China Normal Univ, SCNU Environm Res Inst, Guangdong Prov Key Lab Chem Pollut & Environm Saf, Guangzhou 510006, Guangdong, Peoples R China;[2]South China Normal Univ, SCNU Environm Res Inst, MOE Key Lab Environm Theoret Chem, Guangzhou 510006, Guangdong, Peoples R China;[3]Guangdong Ocean Univ, Fac Chem & Environm Sci, Zhanjiang 524088, Peoples R China;[4]Guangdong Univ Technol, Sch Environm Sci & Engn, Guangzhou 510006, Guangdong, Peoples R China

年份：2019

卷号：683

起止页码：61

外文期刊名：SCIENCE OF THE TOTAL ENVIRONMENT

收录：SCI-EXPANDED(收录号：WOS:000471657600007)、、EI(收录号：20192106964053)、Scopus(收录号：2-s2.0-85065917735)、WOS

基金：The authors would like to acknowledge six anonymous reviewers for their helpful and constructive comments which greatly improved the clarity and quality of the paper. The authors would also like to acknowledge the financial support from the National Natural Science Foundation of China (41807480, 41201522 and U1401235) and Guangdong Provincial Natural Science Foundation (S2012040006898).

语种：英文

外文关键词：Sex ratio; Secondary sex characteristics; Vtg mRNA induction; Androgenic effect; Estrogenic effect

外文摘要：Domestic wastewaters are an important source of endocrine disrupting chemicals in the receiving aquatic environment. Most rural domestic wastewaters (RDWs) in China have been directly discharged into the aquatic environment without any treatment. Here we studied the effects of RDWs on the western mosquitofish (Gambusia affinis) from two rural rivers receiving untreated RDWs. Mosquitofish samples were collected at 5 sampling sites along two rivers during dry and wet seasons. Sex ratios, secondary sex characteristics and transcriptional levels of target genes related to the endocrine systemin adult females and males were determined. In parallel, various pollutants including steroid hormones, phenolic compounds, pesticides, polycyclic aromatic hydrocarbons (PAHs) and heavy metals were measured in the water samples at all sites. The results showed that the androgenic effects in the fish were evidenced by significant increase in male to female ratio in fish populations at two sampling sites and by the presence of modified hemal spines in females at four sampling sites when compared to the reference site. The males from the two rivers had increased Vtg mRNA expressions with a maximal 6.2-fold increase relative to the reference site and a delayed development of hemal spines. The redundancy analysis (RDA) showed that some physiological parameters were related to steroid hormones, phenolic compounds and PAHs. The findings from this study suggest that RDWs can lead to masculinization in females and feminization in males. (C) 2019 Elsevier B.V. All rights reserved.