文献类型：期刊文献

中文题名：罗非鱼皮胶原蛋白肽在润肤霜中的应用及性能评价

英文题名：Application and properties of collagen peptide from tilapia skinin moisturizing cream

作者：李继城[1];孔松芝[1];李东东[2];李思东[1];胡章[1];郭敏慧[1]

机构：[1]广东海洋大学化学与环境学院,广东湛江524088;[2]广东海洋大学海洋与气象学院,广东湛江524088

年份：2018

卷号：39

期号：5

起止页码：23

中文期刊名：食品工业科技

外文期刊名：Science and Technology of Food Industry

收录：CSTPCD、、CSCD_E2017_2018、北大核心2017、北大核心、CSCD

基金：省级大学生创新创业训练计划项目(CXXL2016090);广东海洋大学创新强校工程科研项目(GDOU2016050229);广东省教育厅创新强校工程专项资金项目(2014KZDXM038);广东省科技计划项目(2015A020216019)

语种：中文

中文关键词：罗非鱼皮;胶原蛋白肽;润肤霜;保湿性;抗氧化性;防晒;光老化

外文关键词：tilapia skin; collagen peptide; moisturizing cream; moisture retention; anti - oxidation activity; sunblock; photoaging

中文摘要：本研究采用酶解法从罗非鱼皮中提取胶原蛋白肽,并对其基本成分、分子量分布、抗氧化活性、保湿性以及紫外吸收性能进行考察和分析,同时将提取到的罗非鱼皮肽与羧甲基壳聚糖按不同比例进行复配,应用到润肤霜中并进行性能评价。结果表明:酶解法所提取的罗非鱼皮肽蛋白质含量为94.75%,罗非鱼皮肽中分子量小于1000 Da的组分高达82.27%,平均分子量为614 Da,对OH^-、DPPH·、O_2^-·、清除率的IC_(50)值分别为5.34、5.03、7.63 mg/mL,且具有良好的保湿效果,并对UBC和UVB波段的紫外线有吸收;所制备的润肤霜具有良好的保水和体外抗氧化活性以及防晒功效,其感官和理化指标符合国家润肤霜产品质量标准规定,其中RFS-4的综合效果最佳。通过裸鼠在体皮肤刺激性实验和抗皮肤光老化实验,对比不同组别裸鼠皮肤表征情况,结果表明:自制润肤霜安全无刺激并具有较好的抗皮肤光老化作用。本研究为罗非鱼皮肽在抗光老化日化产品的开发利用提供科学的理论基础。

外文摘要：In this experiment,enzymolysis method was employed to extract collagen peptide from the skin of tilapia.Meanwhile, its fundamental components, molecular weight distribution, anti- oxidation activity, moisture retention and UV absorption properties were also investigated and analyzed.And then the tilapia peptide and carboxymethy] chitosan, which were matched according to different proportions, were applied to prepare moisturizing cream, the properties of which were then evaluated.The result indicated that the content of tilapia skin peptide protein was 94.75% , and the molecular weight of tilapia skin peptide was less than 1000 Da（82.27% ） as well as the average molecular weight was 614 Da.The IC50 values of this peptide on ·OH^- , DPPH· and O2^-· radical scavenging activities were 5.34,5.03 and 7.63 mg/mL, respectively.Moreover, the peptide possessed favourable moisturizing efficacy, as well as UVC and UVB absorbing performance to some extent.The results also revealed that the prepared skin care cream, mainly including the above- mentioned peptide and carboxymethyl chitosan, had good moisturizing and anti- aging efficacy, as well as sunblock effect. Besides, the sensory and physicoehemical property of this cream conformed to the regulation of national moisturizing cream product quality standards.Furthermore, skin irritation and skin anti-photoaging tests were carried out using the nude mice,and the results suggested that this homemade moisturizer was safe and nonirritating, and had prevented skin photoaging efficacy on the basis of comparison between different groups.This study provided a scientific theoretical basis for the development and utilization of tilapia skin peptides in anti-aging products.