文献类型：期刊文献

英文题名：The pearl oyster Pinctada fucata martensii genome and multi-omic analyses provide insights into biomineralization

作者：Du X.; Fan G.; Jiao Y.; Zhang H.; Guo X.; Huang R.; Zheng Z.; Bian C.; Deng Y.; Wang Q.; Wang Z.; Liang X.; Liang H.; Shi C.; Zhao X.; Sun F.; Hao R.; Bai J.; Liu J.; Chen W.; Liang J.; Liu W.; Xu Z.; Shi Q.; Xu X.; Zhang G.; Liu X.

机构：[1]Fishery College, Guangdong Ocean University, Zhanjiang, 524025, China;[2]BGI-Qingdao, Qingdao, 266555, China;[3]BGI-Shenzhen, Shenzhen, 518083, China;[4]Haskin Shellfish Research Laboratory, Department of Marine and Coastal Sciences, Rutgers University, Port Norris, 08349, NJ, United States;[5]Atlantic Cape Community College, Mays Landing, 08330, NJ, United States;[6]Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, 266071, China;[7]Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China;[8]National Local Joint Engineering Laboratory of Ecological Mariculture, Qingdao, 266071, China

年份：2017

卷号：6

期号：8

外文期刊名：GigaScience

收录：Scopus(收录号：2-s2.0-85035049500)

语种：英文

外文关键词：Biomineralization; Genome; Nacre; Pinctada fucata martensii; VWA-containing protein

外文摘要：Nacre, the iridescent material found in pearls and shells of molluscs, is formed through an extraordinary process of matrix-assisted biomineralization. Despite recent advances, many aspects of the biomineralization process and its evolutionary origin remain unknown. The pearl oyster Pinctada fucata martensii is a well-known master of biomineralization, but the molecular mechanisms that underlie its production of shells and pearls are not fully understood. We sequenced the highly polymorphic genome of the pearl oyster and conducted multi-omic and biochemical studies to probe nacre formation. We identified a large set of novel proteins participating in matrix-framework formation, many in expanded families, including components similar to that found in vertebrate bones such as collagen-related VWA-containing proteins, chondroitin sulfotransferases, and regulatory elements. Considering that there are only collagen-based matrices in vertebrate bones and chitin-based matrices in most invertebrate skeletons, the presence of both chitin and elements of collagen-based matrices in nacre suggests that elements of chitin- and collagen-based matrices have deep roots and might be part of an ancient biomineralizing matrix. Our results expand the current shell matrix-framework model and provide new insights into the evolution of diverse biomineralization systems. ? The Author 2017. Published by Oxford University Press.