文献类型：期刊文献

英文题名：Powering shrimp growth: How Atractylodes macrocephala polysaccharide fuels Litopenaeus vannamei development through intestinal microbiota modulation

作者：Chen, Xiping[1,2];Deng, Junming[1,2];Dong, Xiaohui[1,2];Yang, Qihui[1,2];Liu, Hongyu[1,2];Zhang, Shuang[1,2];Xie, Shiwei[1,2];Zhang, Wei[1,2];Tan, Beiping[1,2];Chi, Shuyan[1,2]

机构：[1]Guangdong Ocean Univ, Fisheries Coll, Aquat Nutr & Feed Res Lab, Zhanjiang 524088, Peoples R China;[2]Guangdong Engn Technol Res Ctr Accurate Nutr & Hig, Zhanjiang 524088, Peoples R China

年份：2026

卷号：611

外文期刊名：AQUACULTURE

收录：SCI-EXPANDED(收录号：WOS:001543496700002)、、WOS

基金：The study received funding from China's National Major R & D Proj-ect (Grant No. 2023YFD2402000) .

语种：英文

外文关键词：Litopenaeus vannamei; Low fish meal; Atractylodes macrocephala polysaccharide; Intestinal microbiota; Intestinal barrier

外文摘要：This study investigated how Atractylodes macrocephala polysaccharide (AMP) enhances the growth of Litopenaeus vannamei through modulation of intestinal microbiota. Seven experimental diets were formulated, including a control group (containing 18 % fish meal) and a negative control group (containing 12 % fish meal). Based on the negative control, AMP was supplemented at six graded levels: 0, 100, 300, 500, 700, and 1500 mg/kg. The feeding study spanned 60 days. The results indicated that adding 500 mg/kg of AMP to the diet notably boosted weight gain rate (WGR) while simultaneously reducing the feed conversion ratio (FCR) (P < 0.05) in Litopenaeus vannamei. Additionally, it markedly upregulated the mRNA expression levels of the growth-related genes. AMP supplementation increased the abundance of beneficial bacterial genera (Alistipes, Monoglobus, Bacteroides, and Eubacterium_xylanophilum_group). This improvement enhanced intestinal microbial diversity and functionality while strengthening immune, chemical, and physical barrier functions. Correlation analysis revealed significant positive associations between these beneficial bacterial genera and the levels of intestinal neurotransmitters, digestive enzyme activities, as well as the expression levels of intestinal barrier-related genes. In summary, the administration of an optimal amount of AMP (500 mg/kg) improves the intestinal health of Litopenaeus vannamei through the alteration of its intestinal microbiota, thereby fostering shrimp development.