文献类型：期刊文献

英文题名：Preparation and characterization of a chitosan-gentamicin derivative and its effect on tropical fruit preservation

作者：Liang, Fengyan[1];Li, Xiaohong[1];Li, Xinyi[1];Liu, Xianyou[1];Pan, Rongkai[2];Su, Wenyi[2];Li, Chengpeng[3];Liu, Kaidong[1]

机构：[1]Lingnan Normal Univ, Life Sci & Technol Sch, Zhanjiang 524048, Peoples R China;[2]Lingnan Normal Univ, Sch Chem & Chem Engn, Zhanjiang 524048, Peoples R China;[3]Guangdong Ocean Univ, Sch Chem & Environm Sci, Zhanjiang 524088, Peoples R China

年份：2025

卷号：158

外文期刊名：FOOD HYDROCOLLOIDS

收录：SCI-EXPANDED(收录号：WOS:001290553100001)、、EI(收录号：20243216823633)、Scopus(收录号：2-s2.0-85200328478)、WOS

基金：This work was funded by National Natural Science Foundation of China (No.32372414) , Guangdong Provincial Natural Science Foundation (No. 2022A1515010719; 2023A1515012212) , The Lei Yang Academic Posts Programmer of Lingnan Normal University (No. 2022) , Scientifc research team project of Lingnan Normal University (No. LT2201) , Lingnan Normal University Talent Program (ZL22010) . Provincial college student innovation and entrepreneurship training plan (No.S202310579018) , Guangdong Provincial General University Young Innovative.TalentsProject (2018KQNCX145) .

语种：英文

外文关键词：Chitosan-gentamicin derivative; Water solubility; Antibacterial activity; Tropical fruit preservation

外文摘要：Applications of chitosan (CS) are hindered by its weak antimicrobial ability, poor solubility in basic and neutral solutions, structural modification is needed to improve its functional properties. Herein, a new chitosangentamicin derivative (CS-GT) was successfully synthesized via protection, regioselective bromination, nucleophile substitution reaction, and deprotection. Characterization techniques confirmed the successful introduction of GT onto the C-6 position of CS with a grafting rate of 76.19%. The additional amino groups provided by GT decreased the crystallinity and thermal stability of CS-GT, while enhancing its solubility in neutral and alkaline solutions. Compared to CS, CS-GT exhibited 2.50 and 2.41 times higher antibacterial activities against Escherichia coli and Staphylococcus aureus, , respectively. Besides, an active packaging coating was develop by incorporating glycerol into CS-GT. The hydrogen bond networks formed within coatings endowed them good thermal stability and tightly uniform morphology. Furthermore, increasing CS-GT from 1% to 3% improved the coating's ultraviolet resistance and flexibility, but reduced its waterproof performance, visual appearance, and water barrier properties. Preservation experiments with papaya and litchi showed that CS-GT coatings effectively inhibited microbial growth and maintained quality and appearance up to 16 and 8 days of storage, respectively. In conclusion, CS-GT show promising potential for applications in food packaging.