文献类型：期刊文献

英文题名：Antibiotic susceptibility of Vibrio parahaemolyticus isolated from prawns and oysters marketed in Zhanjiang, China

作者：Li, Yongbin[1];Bi, Siyuan[1,2];Guan, Wenhao[1];Iddrisu, Lukman[1];Wei, Shuai[1];Chen, Yinyan[1];Sun, Lijun[1];Deng, Qi[1];Jiang, Yongqing[2,3];Fang, Zhijia[1];Gooneratne, Ravi[4]

机构：[1]Guangdong Ocean Univ, Key Lab Adv Proc Aquat Prod, Coll Food Sci & Technol, Res Ctr Marine Food,Guangdong Prov Key Lab Aquat P, Zhanjiang 524088, Peoples R China;[2]Shenzhen Jinyue Test Technol Co Ltd, Shenzhen 510100, Peoples R China;[3]Shenzhen Lvshiyuan Biotechnol Co Ltd, Shenzhen 510100, Peoples R China;[4]Lincoln Univ, Dept Wine Food & Mol Biosci, Canterbury 7647, New Zealand

年份：2024

卷号：206

外文期刊名：MARINE POLLUTION BULLETIN

收录：SCI-EXPANDED(收录号：WOS:001274718900001)、、EI(收录号：20242916710590)、Scopus(收录号：2-s2.0-85198544586)、WOS

基金：This work was supported by the Special Fund for the Construction of Common Key Technology Innovation Team of Guangdong Province's Modern Agricultural Industry Technology System (No. 2020KJ151) . Program for Scientific Research Start-up Funds of the Guangdong Ocean University (Nos. R17102 and 060302042008) .r Common Key Technology Innovation Team of Guangdong Province's Modern Agricultural Industry Technology System (No. 2020KJ151) . Program for Scientific Research Start-up Funds of the Guangdong Ocean University (Nos. R17102 and 060302042008) .

语种：英文

外文关键词：Vibrio parahaemolyticus; Antibiotics; Multidrug resistance; Genes; Efflux pump

外文摘要：To evaluate the antibiotic susceptibility of Vibrio parahaemolyticus from prawns and oysters marketed in Zhanjiang, Guangdong, China. 84 strains of V. parahaemolyticus were isolated from prawns and oysters sampled from 9 major markets. The results showed that 84 V. parahaemolyticus strains had the highest rate of antibiotic resistance to oxytetracycline (69.05 %, 58/84) and the lowest rate of antibiotic resistance to enrofloxacin (1.19 %, 1/84), ciprofloxacin (4.76 %, 4/84) and norfloxacin (7.14 %, 6/84) in quinolone. Meanwhile, 96.42 % of the strains showed multiple antibiotic resistance (MAR). PCR results showed that the resistance phenotype was closely related to the antibiotic resistance genes and efflux pump genes (p p < 0.01), and the efflux pump gene was the key causing MAR. The combination of antibiotics significantly eliminated multidrug resistance. In addition, efflux pump inhibitors also reduce MAR. This study may provide information on antibiotic susceptibility, antibiotic resistance and strategies for the control of V. parahaemolyticus. .