文献类型：期刊文献

英文题名：Preparation and Characterization of Nano-Selenium Decorated by Chondroitin Sulfate Derived from Shark Cartilage and Investigation on Its Antioxidant Activity

作者：Chen, Jianping[1,2];Chen, Xuehua[1];Li, Jiarui[1];Luo, Baozhen[1];Fan, Tugui[1];Li, Rui[1,2];Liu, Xiaofei[1,2];Song, Bingbing[1,2];Jia, Xuejing[1,2];Zhong, Saiyi[1,2]

机构：[1]Guangdong Ocean Univ, Coll Food Sci & Technol,Key Lab Adv Proc Aquat Pr, Guangdong Prov Engn Technol Res Ctr Seafood, Guangdong Prov Sci & Technol Innovat Ctr Subtrop, Zhanjiang 524088, Peoples R China;[2]Dalian Polytech Univ, Collaborat Innovat Ctr Seafood Deep Proc, Dalian 116034, Peoples R China

年份：2022

卷号：20

期号：3

外文期刊名：MARINE DRUGS

收录：SCI-EXPANDED(收录号：WOS:000775216200001)、、Scopus(收录号：2-s2.0-85125768702)、WOS

基金：This research was funded by Key-Area Research and Development Program of Guangdong Province (grant number: 2020B1111030004), Guangdong Basic and the Applied Basic Research Foundation (grant number: 2020A1515010860 and 2021A1515012455), the Guangdong Ocean University Innovation Program (grant number: 230419100), the Nanhai Youth Scholar Project of Guangdong Ocean University (grant number: QNXZ201909), the Project of Science and Technology of Zhanjiang City (grant number: 2020A01034), the Scientific Research Foundation of Guangdong Ocean University (grant number: R17034), the Guangdong Province ordinary universities characteristic innovation project (grant number: 2020KTSCX051), and the Guangdong Provincial Department of Education and the Innovative Team Program of High Education of the Guangdong Province (grant number: 2021KCXTD021).

语种：英文

外文关键词：nanoselenium; chondroitin sulfate derived from shark cartilage; structure characterization; antioxidant activity

外文摘要：In the present study, a selenium-chondroitin sulfate (SeCS) was synthesized by the sodium selenite (Na2SeO3) and ascorbic acid (Vc) redox reaction using chondroitin sulfate derived from shark cartilage as a template, and characterized by SEM, SEM-EDS, FTIR and XRD. Meanwhile, its stability was investigated at different conditions of pH and temperatures. Besides, its antioxidant activity was further determined by the DPPH and ABTS assays. The results showed the SeCS with the smallest particle size of 131.3 +/- 4.4 nm and selenium content of 33.18% was obtained under the optimal condition (CS concentration of 0.1 mg/mL, mass ratio of Na2SeO3 to Vc of 1:8, the reaction time of 3 h, and the reaction temperature of 25 degrees C). SEM image showed the SeCS was an individual and spherical nanostructure and its structure was evidenced by FTIR and XRD. Meanwhile, SeCS remained stable at an alkaline pH and possessed good storage stability at 4 degrees C for 28 days. The results on scavenging free radical levels showed that SeCS exhibited significantly higher antioxidant activity than SeNPs and CS, indicating that SeCS had a potential antioxidant effect.