文献类型：期刊文献

英文题名：Assessing effects of guar gum viscosity on the growth, intestinal flora, and intestinal health of Micropterus salmoides

作者：Liu, Yu;Zhou, Hang;Fan, Jiongting;Huang, Huajing;Deng, Junming[1];Tan, Beiping[1]

机构：[1]Guangdong Ocean Univ, Coll Fisheries, Zhanjiang 524088, Peoples R China; Aquat Anim Precis Nutr & High Efficiency Feed Engn, Zhanjiang 524088, Peoples R China; Minist Agr, Key Lab Aquat Livestock & Poultry Feed Sci & Techn, Zhanjiang 524088, Peoples R China

年份：2022

卷号：222

起止页码：1037

外文期刊名：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

收录：SCI-EXPANDED(收录号：WOS:000868953900006)、、EI(收录号：20235015204571)、Scopus(收录号：2-s2.0-85139067712)、WOS

基金：This work was supported by the Program for Scientific Research Startup Funds of Guangdong Ocean University (Grant No. 060302022007); the National Key Research and Development Program of China (Grant No. 2019YFD0900200); the National Natural Science Foundation of China (Grant No. 31760761); the Foundation of Tongwei Co., Ltd. (Grant No. TA2019A003); the Postgraduate Education Innovation Project of Guangdong Ocean University (Grant No. 202246); the Zhanjiang Innovation and Entrepreneurship Team Cultivation "Pilot Program". The authors would like to thank Professor Xiaohui Dong, Shuang Zhang, Dr. Yang Huang, Shuisheng Long, and Dr. Hui Jiang for their assistance.

语种：英文

外文关键词：Micropterus salmoides; Guar gum; Viscous; Intestinal flora; Intestinal health

外文摘要：A 56-day feeding trial was conducted to assess the effects of different viscous guar gum on the growth, intestinal flora, and intestinal health of Micropterus salmoides. Four practical diets with 42.5 % crude protein and 13.7 % crude lipid were formulated to contain 8 % cellulose and three different viscosities (2500, 5200, and 6000 mPa.s) of guar gum. Dietary guar gum inhibits fish growth and feed utilization, decreases the a-diversity of the intestinal flora, and negatively alters the intestinal flora structure and metabolite composition. High viscous guar gum down-regulated the intestinal tight junction, anti-inflammatory, and anti-apoptotic related gene's expression, decreased digesta butyrate/histamine ratio; and increased the abundance of Plesiomonas shigelloides. These results suggest that dietary guar gum adversely affects intestinal health by disrupting intestinal flora structure and metabolite composition, and that viscosity should be considered when using guar gum as a binder in aquafeeds.