文献类型：期刊文献

英文题名：Effects of dietary inclusion of Bacillus amyloliquefaciens AV5 on growth performance, antioxidant activity, innate immune, and hematological responses in Nile tilapia ( Oreochromis niloticus) reared at low and high stocking densities

作者：Shija, Vicent Michael[1,2,3,4];Zhimin, Ju[2];Chen, Huapu[2];Amoah, Kwaku[2,3,4];Li, Yi[2,3,4];Ng'onga, Lishuko[2,3,4];Ndandala, Charles Brighton[2];Zhong, Yong[2,3,4];Masanja, Fortunatus[2];Huang, Junwei[2,3,4];Cai, Jia[1,2,3,4,5,6,7]

机构：[1]Guangdong Ocean Univ, Shenzhen Inst, Shenzhen 518120, Peoples R China;[2]Guangdong Ocean Univ, Coll Fishery, Zhanjiang 524088, Peoples R China;[3]Prov Key Lab Aquat Anim Dis Control & Hlth Culture, Zhanjiang 524088, Peoples R China;[4]Guangdong Key Lab Control Dis Aquat Econ Anim, Zhanjiang 524088, Peoples R China;[5]Southern Marine Sci & Engn Guangdong Lab, Zhanjiang 524002, Peoples R China;[6]Guangxi Key Lab Marine Drugs, Nanning 530200, Peoples R China;[7]Guangxi Acad Sci, Guangxi Beibu Gulf Marine Res Ctr, Nanning 530007, Peoples R China

年份：2025

卷号：156

外文期刊名：FISH & SHELLFISH IMMUNOLOGY

收录：SCI-EXPANDED(收录号：WOS:001368718500001)、、WOS

基金：The authors express their gratitude to all the laboratory members for their valuable suggestions on this work. This research was funded by the National Natural Science Foundation of China (U20A2065, 32073006, 32002426) , Natural Science Foundation of Guangxi (2020GXNSFAA297243) , Natural Science Foundation of Guangdong Province (2021B0202040002) , The Science and Technology Plan of Guangdong province (2023B0202010016) , The Youth Science and Technology Innovation Talent of Guangdong TeZhi plan talent (2023TQ07A888) , Science and Technology Planning Project of Zhan-jiang (2022A01012, 2022A01006) .

语种：英文

外文关键词：Bacillus amyloliquefaciens AV5; Blood; Innate immune response; Nile tilapia; Probiotic; Stocking density

外文摘要：This research work investigated the efficacy of Bacillus amyloliquefaciens AV5 in mitigating the stress effects of stocking densities in Nile tilapia (Oreochromis niloticus). 520 healthy Nile tilapia fingerlings (24.43 +/- 1.4g) were randomly allocated to 16 plastic tanks, each with a capacity of 400L. Two stocking densities were tested: low density (37.5 fish/m(3)) and high density (125 fish/m(3)) with four treatment groups(low density with a control diet (LDC), high density with a control diet (HDC), low density with a supplemented diet (LDS), and high density with a supplemented diet (HDS)) for 8 weeks. HDC exhibited lower values (P < 0.05) for specific growth rate, final weight, weight gain rate, and specific growth rate than fish fed at LDC, LDS, and HDS. The lowest feed conversion ratio was recorded at the LDS and HDS. There were no significant differences (P > 0.05) in survival rates among treatments. There were no notable disparities (P > 0.05) in the LDC, LDS, and HDS body composition. Antioxidant enzyme activities were greater in LDC, LDS, and HDS than in HDC, while malondialdehyde levels were higher in HDC, and hematology parameters in HDS were improved compared to HDC. Elevated levels (P < 0.05) of phagocytic and lysozyme activity were seen in LDS and HDS. There was no change in glucose levels in HDS and LDC. Nonetheless, cortisol was elevated in HDC compared to LDC, LDS, and HDS. Hence, B. amyloliquefaciens AV5(1 x 10(8) cfu/g) is a potential probiotic to alleviate HDC-induced stress in O. niloticus.