文献类型：期刊文献

英文题名：Absorption, metabolism and bioavailability of flavonoids: a review

作者：Chen, Lei[1];Cao, Hui[1];Huang, Qun[2,3];Xiao, Jianbo[1,4];Teng, Hui[1]

机构：[1]Guangdong Ocean Univ, Coll Food Sci & Technol, Zhanjiang 524025, Peoples R China;[2]Guizhou Med Univ, Sch Publ Hlth, Key Lab Environm Pollut Monitoring & Dis Control, Minist Educ, Guiyang, Peoples R China;[3]Chengdu Univ, Sch Food & Biol Engn, Meat Proc Key Lab Sichuan Prov, Chengdu, Peoples R China;[4]Jinan Univ, Inst Food Safety & Nutr, Guangzhou 510632, Peoples R China

年份：0

外文期刊名：CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

收录：SCI-EXPANDED(收录号：WOS:000657536700001)、、EI(收录号：20212410488269)、Scopus(收录号：2-s2.0-85107494390)、WOS

基金：This work is supported by the National Natural Science Foundation of China (NSFC, Grant No. 31801459; NSFC, Grant No. 32072209), Science and Technology General Projects of Fujian Province (2019J01393), Educational research project for young and middle-aged teachers in Fujian Province (JT180116).

语种：英文

外文关键词：Flavonoids; absorption; activity; metabolism; bioavailability

外文摘要：Flavonoids are stored in various plants and widely presented in different kinds of food in variable amounts. Plant roots, stems, leaves, flowers and fruits are known to have high amounts of flavonoids. However, flavonoid aglycones are found less frequently in natural products, as it requires bioconversion through bacteria, which provide beta-glucosidase to convert them. Recently, flavonoids and its metabolites were applied in the prevention and treatment of various diseases such as cancers, obesity, diabetes, hypertension, hyperlipidemia, cardiovascular diseases, neurological disorders and osteoporosis in numerous studies. This review focused on absorption, activity, metabolism, and bioavailability of flavonoids. Also authors organized and collected newly-found reports of flavonoids and their absorption barriers of flavonoids in the gastrointestinal tract, providing the latest findings and evidence from the past decade. Particularly, nanoparticles delivery systems are emphasized regarding fabrication methods and their potential benefits on flavonoids. Moreover, the potential challenges of nanoparticles as delivery system for flavonoids in the gastrointestinal tract are also discussed.