文献类型：期刊文献

中文题名：华贵栉孔扇贝肉及其酶解产物对半去势雄性大鼠生殖能力的影响

英文题名：Effects of Chlamys nobilis and its enzymatic hydrolysates on reproductive capacity of hemi-castrated male rats

作者：郑环宇[1];高加龙[1,2];章超桦[1,2];司蕊[1];郑惠娜[1,2];曹文红[1,2];秦小明[1,2]

机构：[1]广东海洋大学食品科技学院/国家贝类加工技术研发分中心(湛江)/广东省水产品加工与安全重点实验室/广东省海洋生物制品工程实验室/水产品深加工广东普通高等学校重点实验室,广东湛江524088;[2]大连工业大学/海洋食品精深加工关键技术省部共建协同创新中心,辽宁大连116034

年份：2021

卷号：17

期号：3

起止页码：94

中文期刊名：南方水产科学

外文期刊名：South China Fisheries Science

收录：CSTPCD、、CSCD2021_2022、北大核心、CSCD、北大核心2020

基金：财政部和农业农村部国家现代农业产业技术体系资助(CARS-49);广东普通高等学校水产品高值化加工与利用创新团队项目(GDOU2016030503);海洋贝类营养健康食品关键技术及产业化(GDOU2017052606)。

语种：中文

中文关键词：华贵栉孔扇贝;酶解产物;生殖能力;雄性激素

外文关键词：Chlamys nobilis;Enzymatic hydrolysis;Reproductive capacity;Androgen

中文摘要：为探究华贵栉孔扇贝(Chlamys nobilis)肉及其酶解产物对改善男性生殖能力的功效,该研究以半去势SD雄性大鼠为动物实验模型,考察华贵栉孔扇贝肉及其酶解产物对半去势雄性大鼠的性行为表现、脏器系数、血清性激素水平、阴茎组织一氧化氮(NO)和总一氧化氮合酶(NOS)活力等的影响。结果表明,华贵栉孔扇贝肉及其酶解产物可缩短半去势雄性大鼠的勃起潜伏期(P<0.01),增加扑捉次数(P<0.05)、骑乘次数(P<0.05)等性行为表现;显著提升半去势雄性大鼠的睾丸、前列腺-精囊腺系数(P<0.05),能显著提高半去势大鼠血清睾酮(T)含量,稳定黄体生成素(LH)和促卵泡激素(FSH)水平(P<0.05);同时能显著介导NO和NOS的生成。综上,华贵栉孔扇贝肉及其酶解产物对半去势雄性大鼠的生殖能力有一定改善作用,其改善机制可能与调节半去势雄性大鼠血清性激素、促进阴茎信号因子的生成有关。

外文摘要：To explore the ameliorative effect of Chlamys nobilis and its enzymatic hydrolysates on male sexual function,we investigated the sexual behaviors,organ coefficient,level of serum sex hormone,NO contents and enzyme activity of NOS in penile tissue of the hemi-castrated male SD rats.The results show that C.nobilis and its enzymatic hydrolysates could increase the sexual behaviors of hemi-castrated male rats,such as catching frequency(P<0.05)and mount frequency(P<0.05);decrease the errection latency significantly(P<0.01);and increase the coefficients of testicular and prostate-seminal gland in hemi-castrated male rats significantly(P<0.05).Besides,it could increase the serum testosterone content,stable the levels of luteinizing hormone(LH)and follicle stimulating hormone(FSH).Moreover,it could mediate the production of NO and NOS in penile tissue significantly(P<0.05).Therefore,C.nobi-lis and its enzymatic hydrolysates can improve the reproductive capacity of hemi-castrated male rats,and the improvement mechan-ism is probably related to the regulation of serum sex hormones and the promotion of signal factors of penile tissue in hemi-castrated male rats.