文献类型：期刊文献

英文题名：Effects of chromium picolinate on fat deposition, activity and genetic expression of lipid metabolism-related enzymes in 21 day old Ross broilers

作者：Chen, Guangxin[1,2,3];Gao, Zhenhua[3];Chu, Wenhui[1,2];Cao, Zan[3];Li, Chunyi[1,2];Zhao, Haiping[1,2]

机构：[1]State Key Lab Special Anim Mol Biol, Changchun 130112, Jilin, Peoples R China;[2]Chinese Acad Agr Sci, Inst Special Anim & Plant Sci, Changchun 130112, Jilin, Peoples R China;[3]Guangdong Ocean Univ, Coll Agr, Zhanjiang 524000, Peoples R China

年份：2018

卷号：31

期号：4

起止页码：569

外文期刊名：ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES

收录：SCI-EXPANDED(收录号：WOS:000425889000014)、、Scopus(收录号：2-s2.0-85042879650)、WOS

基金：We wish to thank our colleagues of Deer Antler Research Group at Chinese Academy of Agricultural Sciences and classmates of Guangdong Ocean University for their contributions to the study. The researches that are involved in this review are funded by State 863 Project (2011AA100603) and "The research and application of feed additives to improve quality of muscles".

语种：英文

外文关键词：Ross Broiler; Chromium Picolinate (CrP); Fatty Acid Synthase; Acetyl-CoA Carboxylase; Hormone-sensitive Lipase; Lipoprotein Lipase; Enzymatic Activity; mRNA Expression

外文摘要：Objective: This experiment was conducted to investigate the effects of chromium picolinate (CrP) on fat deposition, genetic expression and enzymatic activity of lipid metabolism-related enzymes. Methods: Two hundred forty one-day-old Ross broilers were randomly divided into 5 groups with 4 replicates per group and 12 Ross broiler chicks per replicate. The normal control group was fed a basal diet, and the other groups fed the same basal diet supplemented with 0.1, 0.2, 0.4, and 0.8 mg/kg CrP respectively. The experiment lasted for 21 days. Results: Added CrP in the basal diet decreased the abdominal fat, had no effects on subcutaneous fat thickness and inter-muscular fat width; 0.2 mg/kg CrP significantly decreased the fatty acid synthase (FAS) enzymatic (p< 0.05); acetyl-CoA carboxylase (ACC) enzymatic activity decreased in all CrP groups (p< 0.05); hormone-sensitive lipase (HSL) enzymatic activity also decreased, but the change was not significant (p> 0.05); 0.4 mg/kg CrP group sig-nificantly decreased the lipoprotein lipase (LPL) enzymatic activity. FAS mRNA expression increased in all experimental groups, and the LPL mRNA expression significantly increased in all experimental groups (p< 0.05), but not 0.2 mg/kg CrP group. Conclusion: The results indicated that adding CrP in basal diet decreased the abdominal fat percentage, had no effects on subcutaneous fat thickness and inter-muscular fat width, decreased the enzymatic activity of FAS, ACC, LPL and HSL and increased the genetic expression levels of FAS and LPL.