文献类型：期刊文献

英文题名：The structural characteristics, biological activities and mechanisms of bioactive brown seaweed polysaccharides: A review

作者：Zhou, Qing-Ling[1];Wang, Zhuo[1];Chen, Wen-Ting[1];Liu, Xiao-Fei[1];Cheong, Kit-Leong[1];Zou, Yu-Xiao[2];Zhong, Sai-Yi[1,3];Li, Rui[1,3]

机构：[1]Guangdong Ocean Univ, Coll Food Sci & Technol, Guangdong Prov Engn Technol Res Ctr Seafood, Guangdong Prov Sci & Technol Innovat Ctr Subtrop F, Zhanjiang 524088, Peoples R China;[2]Guangdong Acad Agr Sci, Minist Agr, Sericultural & Agrifood Res Inst, Key Lab Funct Foods, Guangzhou 510640, Peoples R China;[3]Dalian Polytech Univ, Collaborat Innovat Ctr Seafood Deep Proc, Dalian 116034, Peoples R China

年份：2024

卷号：119

外文期刊名：JOURNAL OF FUNCTIONAL FOODS

收录：SCI-EXPANDED(收录号：WOS:001257913700001)、、Scopus(收录号：2-s2.0-85196012255)、WOS

基金：This work was funded by the Guangdong Basic and Applied Basic Research Foundation (2023A1515010005), the Special Funds for Universities in Guangdong Province in the Key Areas of Biomedicine and Health (2023ZDZX2025), the Open Project of Key Laboratory of Functional Food, Ministry of Agriculture (202107), and the Program for Scientific Research Start-up Funds of Guangdong Ocean University (R20078, R19017), and the Innovative Team Program of High Education of Guangdong Province (2021KCXTD021).

语种：英文

外文关键词：Brown seaweed; Polysaccharide; Action mechanism; Fucoidan; Alginate; Laminarin

外文摘要：Brown seaweed polysaccharides (BSPs) are potential alternative sources of bioactive compounds. The food and pharmaceutical industries have a great interest in BSPs because of their various bioactivities, such as anticancer, antioxidant, and immunomodulatory activities. Studies have demonstrated that the bioactivities of BSPs are significantly influenced by their structural characteristics and chemical constitution; but, their specific conformational relationships are complex and required further study. However, systematic reviews of the biological activities and mechanisms of action of BSPs are currently inadequate. Thus, this paper summarizes recent studies on the physicochemical and structural features, characterization methods, biological activities, and related action mechanisms of BSPs from different sources. Based on these findings, future prospects include the following three aspects. More advanced research techniques need to be developed to identify the exact main and branch structure of BSPs; in-depth studies of the detailed structure of BSPs are needed to elucidate the conformational relationships between polysaccharides and their activities, and clinical trials should be conducted to verify the effectiveness of BSPs in the prevention and treatment of various diseases. The information provided here aims to offer a theoretical foundation for further research on the structural properties, mechanism of action, and potential applications of BSPs in food and pharmaceutical industries as well as, to increase the economic value of BSPs and extend their application range.