文献类型：期刊文献

英文题名：Chitosan-Based Composite Materials for Prospective Hemostatic Applications

作者：Hu, Zhang[1];Zhang, Dong-Ying[1];Lu, Si-Tong[1];Li, Pu-Wang[2];Li, Si-Dong[1]

机构：[1]Guangdong Ocean Univ, Sch Chem & Environm Sci, Dept Appl Chem, Zhanjiang 524088, Guangdong, Peoples R China;[2]Chinese Acad Trop Agr Sci, Agr Prod Proc Res Inst, Zhanjiang 524001, Guangdong, Peoples R China

年份：2018

卷号：16

期号：8

外文期刊名：MARINE DRUGS

收录：SCI-EXPANDED(收录号：WOS:000456736900025)、、Scopus(收录号：2-s2.0-85053716926)、WOS

基金：Guangdong Provincial Natural Science Foundation of China (2016A030308009), Project of Science and Technology Plan of Guangdong Province (2015A020216019, 2017A010103023) and Project of Enhancing School with Innovation of Guangdong Ocean University (2017KTSCX090).

语种：英文

外文关键词：chitosan; composite materials; hemostasis; mechanisms; films; sponges; hydrogels; particles; fibers; applications

外文摘要：Effective hemostasis is vital to reduce the pain and mortality of patients, and the research and development of hemostatic materials are prerequisite for effective hemostasis. Chitosan (CS), with good biodegradability, biocompatibility and non-toxicity, has been widely applied in bio-medicine, the chemical industry, the food industry and cosmetics. The excellent hemostatic properties of CS have been extensively studied. As a result, chitosan-based composite hemostatic materials have been emerging. In this review, the hemostatic mechanism of chitosan is briefly discussed, and then the progress of research on chitosan-based composite hemostatic materials with multiple forms such as films, sponges, hydrogels, particles and fibers are introduced. Finally, future perspectives of chitosan-based composite hemostatic materials are given. The objective of this review is to provide a reference for further research and development of effective hemostatic materials.