文献类型：期刊文献

英文题名：Adapting to hypo-salinity: Molecular mechanisms in giant clams and symbionts with implications for coral reef resilience under climate change

作者：Zhao, Zhen[1,2,3,4,5,6];Duan, Xixi[1,2,3,4,5,6];Zhang, Tao[2,3,4,5,6];Bi, Siqi[2];Noor, Zohaib[2,3,4,5];Guo, Shuming[2,3,4];Wei, Zonglu[1,2,3,4,5,6];Zhang, Yinjie[1,2,3,4,5,6];Qin, Yanping[2,3,4];Ma, Haitao[2,3,4,5,6];Pan, Ying[1];Yu, Ziniu[2,3,4,5,6];Li, Jun[2,3,4,5,6];Zhang, Yuehuan[2,3,4,5,6]

机构：[1]Guangxi Univ, Coll Anim Sci & Technol, Nanning 530004, Peoples R China;[2]Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, Guangdong Prov Key Lab Appl Marine Biol,Key Lab Br, Guangzhou 510301, Peoples R China;[3]Guangdong Ocean Univ, Shenzhen Inst, Shenzhen 518120, Peoples R China;[4]Chinese Acad Sci, Key Lab Trop Marine Biotechnol Hainan Prov, Sanya Natl Marine Ecosyst Res Stn, Trop Marine Biol Res Stn Hainan,Sanya Inst Ocean E, Sanya 572000, Peoples R China;[5]Agrotech Extens Ctr Guangdong Prov, Guangzhou 510145, Peoples R China;[6]Chinese Acad Sci, South China Sea Inst Oceanol, Daya Bay Marine Biol Res Stn, Shenzhen 518124, Peoples R China

年份：2025

卷号：285

外文期刊名：ENVIRONMENTAL RESEARCH

收录：SCI-EXPANDED(收录号：WOS:001542383900008)、、EI(收录号：20253018853443)、WOS

基金：This research was supported by National Key Research and Development Program of China (2021YFC3100504) ; International Partnership Program of Chinese Academy of Sciences (133244KYSB20200007) ; Hainan Provincial Key R & D Programme (ZDYF2024XDNY175; ZDYF2025XDNY088) ; Shenzhen Basic Research Project (JCYJ20240813111707010) ; Guangdong Science and Technology Plan Programme (2024B1212050006) ; Guangzhou Science and Technology Project (202206010133; 2023B03J00165; 2024B03J1226) ; Guangdong Basic and Applied Basic Research Foundation (2023A1515010944; 2022A1515010203) ; Research on breeding technology of candidate species for Guangdong modern marine ranching (2024-MRB-00-001) ; National Marine Genetic Resource Center; the earmarked fund for CARS-49; China Postdoctoral Science Foundation (2024M763365) ; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai) (No. SML2023SP234) and the Science and Technology Planning Project of Guangdong Province, China (2023B1212060047) .

语种：英文

外文关键词：Tridacna crocea; Hypo-salinity; Meta-transcriptome; Zooxanthellae; Symbiosis

外文摘要：Typhoon climates and extreme rainy seasons drive changes in seawater salinity and quality, threatening coral reef ecosystems. As key contributors to coral reef ecosystems, giant clams face major survival pressures from salinity fluctuations. Understanding their salinity adaptation and recovery strategies is thus critical for the longterm conservation and sustainable management of coral reefs. Here, we integrated physiological and metatranscriptomic analyses to investigate responses of Tridacna crocea to hypo-saline conditions (20 ppt, 27 ppt) and subsequent recovery at 34 ppt. Hypo-salinity significantly reduced growth and survival, with only 69 % survival at 20 ppt, while elevated sodium-potassium pump (NKA) activity was observed, facilitating ion balance maintenance. Meta-transcriptomic analysis revealed downregulated genes related to antioxidants (GGT1), ABC transporters (ABCB11, ABCA12), and fatty acid metabolism (ACAA1), alongside upregulated genes involved in amino acid metabolism (AGXT2, ALDH4A1). Symbionts exhibited decreased photosystem II (PSII) activity, reactive oxygen species (ROS) accumulation, and expulsion. Notably, partial recovery was achieved under 27 ppt hypo-salinity, whereas 20 ppt induced irreversible damage. Collectively, T. crocea copes with hypo-saline stress through coordinated regulation of ion transport, amino acid metabolism, and symbiont functionality, with 27 ppt potentially emerging as a critical threshold for recoverable adaptation. These findings provide valuable mechanistic insights to inform coral reef conservation strategies under global climate change.