文献类型：期刊文献

英文题名：A simple and efficient method for synthesis of fluorine-containing saccharide esters and antiviral activity

作者：Chen, Hong; Huang, Si-Qing; Xie, Jian-Ying

机构：[1]Guangdong Ocean Univ, Dept Appl Chem, Zhanjiang 524088, Peoples R China

年份：2006

卷号：127

期号：8

起止页码：1130

外文期刊名：JOURNAL OF FLUORINE CHEMISTRY

收录：SCI-EXPANDED(收录号：WOS:000239874500018)、、Scopus(收录号：2-s2.0-33746341182)、WOS

语种：英文

外文关键词：fluorine-containing benzoic acid; O-acetylglycosyl saccharide esters; TMV; DMAP/Et3N

外文摘要：Sixteen new fluorine-containing saccharide esters from fluorine-containing benzoic acids and alpha-O-acetylglycosyl bromide were synthesized in the presence of 4-dimethylaminopyridine (DMAP) and triethylamine (Et3N) under mild conditions in good yields and their structures were clearly verified by IR, H-1 NMR, MS and elemental analysis. This method has high stereospecificity, the configuration is unitary, the new synthesized compounds are all of beta-configuration. The results of bioassay showed that these title compounds possess potential antiviral activities against tobacco mosaic virus (TMV). (c) 2006 Elsevier B.V. All rights reserved.