详细信息
翡翠贻贝糖胺聚糖的制备及其生理活性初探 被引量:27
Primary exploration for extractiong technology and physiological activity of Perna viridis glycosaminoglycan
文献类型:期刊文献
中文题名:翡翠贻贝糖胺聚糖的制备及其生理活性初探
英文题名:Primary exploration for extractiong technology and physiological activity of Perna viridis glycosaminoglycan
作者:洪鹏志[1];章超桦[1];吴红棉[1];杨文鸽[2];郝记明[1];张静[1]
机构:[1]湛江海洋大学食品科学与工程系,广东湛江524025;[2]宁波大学生命科学与生物工程学院,浙江宁波315211
年份:2001
卷号:10
期号:2
起止页码:158
中文期刊名:上海水产大学学报
外文期刊名:Journal of Shanghai Fisheries University
收录:CSTPCD、、CSCD_E2011_2012、CSCD
基金:国家教委留学回国人员资助项目 ( 1993-36 0 )
语种:中文
中文关键词:翡翠贻贝;糖胺聚糖;蛋白酶;水解法;提取;抗肿瘤活性
外文关键词:Perna viridis;glycosaminoglycan;proteinase hydrolization method;Extration;antitumor activity
中文摘要:探讨了翡翠贻贝中提取糖胺聚糖的蛋白酶水解及乙醇沉淀等条件。所制备的翡翠贻贝糖胺聚糖含GAG72 .1% ,经动物实验 ,当剂量为 80mg/kg体重时 ,对昆明小鼠移植性肿瘤S - 180的抑瘤率可达 5 2 .4% 。
外文摘要:The extraction of glycosaminoglycan(GAG) from Perna virids was studied.The conditions for proteinase hydrolysis and the deposition with ethanol were proposed.The findings in antitumor test indicated the inhibition rate on Sarcoma 180 was 52.4% when the dosage of P. viridis glycosaminoglycan used was 80 mg/kg,and the weight of spleen (immunity organ) in mice was obviously increased.
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