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Interactions between host and gut microbiota in domestic pigs: a review
GUT MICROBESPatil, Yadnyavalkya Gooneratne, Ravi Ju, Xiang-Hong  出版年:2020
It is well established that pig gut microbiota plays a critical role in maintaining metabolic homeostasis as well as in a myriad of physiological, neurological and immunological functions; including protection from patho...
Chitosan oligosaccharide-mediated attenuation of LPS-induced inflammation in IPEC-J2 cells is related to the TLR4/NF-κB signaling pathway
CARBOHYDRATE POLYMERSShi, Lin Fang, Biao Yong, Yanhong Li, Xuewen Gong, Dongliang Li, Junyu Yu, Tianyue Gooneratne, Ravi Gao, Zhenhua Li, Sidong Ju, Xianghong  出版年:2019
The protective mechanism of chitosan oligosaccharide (COS) against lipopolysaccharides (LPS) -induced inflammatory responses in IPEC-J2 and in mice with DSS dextran sulfate sodium (DSS) -induced colitis is reported. Upon...
Developmental toxicity, oxidative stress, and related gene expression induced by dioxin-like PCB 126 in zebrafish (<i>Danio rerio</i>)
ENVIRONMENTAL TOXICOLOGYLiu, Han Nie, Fang-Hong Lin, Hong-Ying Ma, Yi Ju, Xiang-Hong Chen, Jin-Jun Gooneratne, Ravi  出版年:2016
3,3,4,4,5-Pentachlorobiphenyl (PCB126) cause multiple adverse effects in organisms including animals and humans. Although PCB toxicities are linked to oxidative damage in rodents, the mechanism in early life stages of ze...
A Comprehensive Analysis of the Colonic Flora Diversity, Short Chain Fatty Acid Metabolism, Transcripts, and Biochemical Indexes in Heat-Stressed Pigs
FRONTIERS IN IMMUNOLOGYHu, Canying Niu, Xueting Chen, Shengwei Wen, Jiaying Bao, Minglong Mohyuddin, Sahar Ghulam Yong, Yanhong Liu, Xiaoxi Wu, Lianyun Yu, Zhichao Ma, Xinbin Ju, Xianghong  出版年:2021
Heat stressed pigs show typical characteristics of inflammatory bowel disease (IBD). However, little is known about the pathogenesis of heat stress (HS)-induced IBD in pigs. In this study, we determined the effects of HS...
Developmental toxicity, EROD, and <i>CYP1A</i> mRNA expression in zebrafish embryos exposed to dioxin-like PCB126
ENVIRONMENTAL TOXICOLOGYLiu, Han Nie, Fang-Hong Lin, Hong-Ying Ma, Yi Ju, Xiang-Hong Chen, Jin-Jun Gooneratne, Ravi  出版年:2016
Dioxin-like PCB126 is a persistent organic pollutant that causes a range of syndromes including developmental toxicity. Dioxins have a high affinity for aryl hydrocarbon receptor (AhR) and induce cytochrome P4501A (CYP1A...
Heat Stress-Induced Dysbiosis of Porcine Colon Microbiota Plays a Role in Intestinal Damage: A Fecal Microbiota Profile
FRONTIERS IN VETERINARY SCIENCEHu, Canying Patil, Yadnyavalkya Gong, Dongliang Yu, Tianyue Li, Junyu Wu, Lianyun Liu, Xiaoxi Yu, Zhichao Ma, Xinbing Yong, Yanhong Chen, Jinjun Gooneratne, Ravi Ju, Xianghong  出版年:2022
The pathological mechanisms of gastrointestinal disorders, including inflammatory bowel disease (IBD), in pigs are poorly understood. We report the induction of intestinal inflammation in heat-stressed (HS) pigs, fecal m...
Tea Tree Oil Terpinen-4-ol Protects Gut Barrier Integrity by Upregulation of Tight Junction Proteins <i>via</i> the ERK1/2-Signaling Pathway
FRONTIERS IN NUTRITIONYong, Yanhong Fang, Biao Huang, Yingxin Li, Junyu Yu, Tianyue Wu, Lianyun Hu, Canying Liu, Xiaoxi Yu, Zhichao Ma, Xingbin Gooneratne, Ravi Li, Sidong Abd El-Aty, A. M. Ju, Xianghong  出版年:2022
Tea tree oil (TTO) exhibits a potent antioxidant, antibacterial, and anti-inflammatory activity and is commonly used in skincare products. However, it is not clear whether TTO can protect gut barrier damage in inflammato...
Gut bacteria formation and influencing factors
FEMS MICROBIOLOGY ECOLOGYYang, Jing Wu, Jin'en Li, Yating Zhang, Yong'e Cho, William C. Ju, Xianghong van Schothorst, Evert M. Zheng, Yadong  出版年:2021
The gut microbiota plays an important role in human health. In modern life, with the improvement of living conditions, the intake of high-sugar and high-fat diets as well as the large-scale use of antibacterial drugs hav...
Proteomic study of hypothalamus in pigs exposed to heat stress
BMC VETERINARY RESEARCHYu, Tian-yue Yong, Yan-hong Li, Jun-yu Fang, Biao Hu, Can-ying Wu, Lian-yun Liu, Xiaoxi Yu, Zhichao Ma, Xingbin Patil, Yadnyavalkya Gooneratne, Ravi Ju, Xiang-hong  出版年:2020
Background With evidence of warming climates, it is important to understand the effects of heat stress in farm animals in order to minimize production losses. Studying the changes in the brain proteome induced by heat st...
Proteomic profiling of serum extracellular vesicles identifies diagnostic markers for echinococcosis
PLOS NEGLECTED TROPICAL DISEASESGuo, Xiaola Wang, Shuai Zhang, Junmei Li, Rui Zhang, Yong'e Wang, Zhengrong Kong, Qingming Cho, William C. Ju, Xianghong Shen, Yujuan Zhang, Lingqiang Fan, Haining Cao, Jianping Zheng, Yadong  出版年:2022
Echinococcosis is a parasitic disease caused by the metacestodes of Echinococcus spp. The disease has a long latent period and is largely underdiagnosed, partially because of the lack of effective early diagnostic approa...
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