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16 条 记 录,以下是 1-16

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Anti-Aging Effect of Chitosan Oligosaccharide on D-Galactose-Induced Subacute Aging in Mice
MARINE DRUGSKong, Song-Zhi Li, Ji-Cheng Li, Si-Dong Liao, Ming-Neng Li, Cheng-Peng Zheng, Pin-Jin Guo, Min-Hui Tan, Wei-Xiang Zheng, Zhao-Hui Hu, Zhang  出版年:2018
Chitosan oligosaccharide (COS), a natural polysaccharide with good antioxidant and anti-inflammatory properties, is the depolymerized product of chitosan possessing various biological activities. The present study was de...
Anti-photoaging effects of chitosan oligosaccharide in ultraviolet-irradiated hairless mouse skin
EXPERIMENTAL GERONTOLOGYKong, Song-Zhi Li, Dong-Dong Luo, Hui Li, Wen-Jie Huang, Yong-Mei Li, Ji-Cheng Hu, Zhang Huang, Na Guo, Min-Hui Chen, Yao Li, Si-Dong  出版年:2018
Skin photoaging (SP) is a premature skin-aging damage after repeated exposure to ultraviolet (UV) radiation, mainly characterized by oxidative stress and inflammatory disequilibrium, which makes skin show the typical sym...
Investigation of the Effects of Molecular Parameters on the Hemostatic Properties of Chitosan
MOLECULESHu, Zhang Lu, Sitong Cheng, Yu Kong, Songzhi Li, Sidong Li, Chengpeng Yang, Lei  出版年:2018
Hemorrhea is one of the major problems in war, trauma care, and surgical operation that threaten the life of the injured and patients. As a novel polymeric hemostatic agent, biodegradable chitosan can stop bleeding throu...
Preparation of nano-hydroxyapatite/chitosan/tilapia skin peptides hydrogels and its burn wound treatment
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESOuyang Qianqian Kong Songzhi Huang Yongmei Ju Xianghong Li Sidong Li Puwang Luo Hui  出版年:2021
There is an urgent need for wound dressings to treat partial-thickness burns. Hydrogels are a promising material that can maintain hydration to promote necrotic tissue removal. Tilapia peptides (TP) and hydroxyapatite (H...
Gastric acid-response chitosan/alginate/tilapia collagen peptide composite hydrogel: Protection effects on alcohol-induced gastric mucosal injury
CARBOHYDRATE POLYMERSLu, Sitong Kong, Songzhi Wang, Ye Hu, Zhang Zhang, Lingyu Liao, Mingneng  出版年:2022
Long-term excessive alcohol intake can easily lead to gastritis, gastric ulcer, and gastric bleeding. In this paper, the gastric acid-responsive hydrogel of CS-NAC/alginate/tilapia collagen peptide (CS-NAC/ALG/TCP) was d...
Chitosan-Gentamicin Conjugate Hydrogel Promoting Skin Scald Repair
MARINE DRUGSYan, Tingting Kong, Songzhi Ouyang, Qianqian Li, Chengpeng Hou, Tingting Chen, Yu Li, Sidong  出版年:2020
Our earlier research indicated that chitosan-gentamicin conjugate (CS-GT) possesses superior antimicrobial activity and good water solubility. To develop CS-GT-based scald dressings, the antibacterial properties of CS-GT...
Preparation and evaluation of squid ink polysaccharide-chitosan as a wound-healing sponge
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONSHuang, Na Lin, Jiali Li, Sidong Deng, Yifeng Kong, Songzhi Hong, Pengzhi Yang, Ping Liao, Mingneng Hu, Zhang  出版年:2018
A new type of wound healing agent was developed using two marine biomaterials (squid ink polysaccharide and chitosan) as carriers and calcium chloride as an initiator for coagulation. Based on central composite design re...
Protective effects of collagen polypeptide from tilapia skin against injuries to the liver and kidneys of mice induced by D-galactose
BIOMEDICINE & PHARMACOTHERAPYLi, Dong-Dong Li, Wen-Jie Kong, Song-Zhi Li, Si-Dong Guo, Jia-Qi Guo, Min-Hui Cai, Ting-Ting Li, Ning Chen, Ri-Zhi Luo, Rong-Qiong Tan, Wei-Xiang  出版年:2019
We wished to investigate the role of a tilapia skin collagen polypeptide (TSCP; molecular weight < 3 kDa) in alleviating liver and kidney injuries in aging mice induced by D-galactose (D-gal) and its underlying mechanism...
Effects of Chitosan-Gentamicin Conjugate Supplement on Non-Specific Immunity, Aquaculture Water, Intestinal Histology and Microbiota of Pacific White Shrimp (<i>Litopenaeus vannamei</i>)
MARINE DRUGSLiang, Fengyan Li, Chengpeng Hou, Tingting Wen, Chongqing Kong, Songzhi Ma, Dong Sun, Chengbo Li, Sidong  出版年:2020
When the aquaculture water environment deteriorates or the temperature rises, shrimp are susceptible to viral or bacterial infections, causing a large number of deaths. This study comprehensively evaluated the effects of...
Use of 18β-glycyrrhetinic acid nanocrystals to enhance anti-inflammatory activity by improving topical delivery
COLLOIDS AND SURFACES B-BIOINTERFACESQuan, Weiyan Kong, Songzhi Ouyang, Qianqian Tao, Jinlong Lu, Sitong Huang, Yongmei Li, Sidong Luo, Hui  出版年:2021
18 beta-Glycyrrhetinic acid (GA) is often topically applied in clinical treatment of inflammatory skin diseases. However, GA has poor solubility in water, which results in poor skin permeability and low bioavailability. ...
Grafting of 18β-Glycyrrhetinic Acid and Sialic Acid onto Chitosan to Produce a New Amphipathic Chitosan Derivative: Synthesis, Characterization, and Cytotoxicity
MOLECULESQuan, Wei-Yan Kong, Song-Zhi Li, Si-Dong Liu, Hua-Zhong Ouyang, Qian-Qian Huang, Yong-Mei Luo, Hui  出版年:2021
Chitosan is the only cationic polysaccharide found in nature. It has broad application prospects in biomaterials, but its application is limited due to its poor solubility in water. A novel chitosan derivative was synthe...
Preparation of Cod Skin Collagen Peptides/Chitosan-Based Temperature-Sensitive Gel and Its Anti-Photoaging Effect in Skin
DRUG DESIGN DEVELOPMENT AND THERAPYKong, Songzhi Lv, Lijiao Guo, Jiaqi Yang, Xiaohong Liao, Mingneng Zhao, Tianyang Sun, Haiyang Zhang, Shuqun Li, Wenjie  出版年:2023
Background: Photoaging decreases quality of life and increases the risk of skin cancer, underscoring the urgent need to explore natural, high-efficacy, anti-skin photoaging (SP) active substances. Methods: In this study,...
Hepatoprotective Effect of Ultrafine Powder of <i>Dendrobium officinale</i> against Acetaminophen-Induced Liver Injury in Mice
FOOD SCIENCE AND TECHNOLOGY RESEARCHKong, Song-Zhi Lin, Guo-Sheng Liu, Jing-Jing Su, Ling-Ye Zeng, Lei Luo, Dan-Dan Su, Zi-Ren Wang, Hong-Feng  出版年:2018
The aim of this study was to investigate the hepatoprotective effect of ultrafine powder of Dendrobium officinale (UDO) against acetaminophen (APAP)-induced liver injury in mice. ICR mice were orally administered with UD...
Optimized preparation of gastric acid-response sulfhydryl functionalized chitosan/alginate/tilapia peptide hydrogel and its protective effects on alcohol-induced liver and brain injury
RSC ADVANCESLu, Sitong Zhang, Lingyu Hu, Zhang Kong, Songzhi Zhang, Zhaoyu Li, Guangfa  出版年:2021
Long-term alcohol intake or drinking large quantities of alcohol at one time can cause organ damage, which in turn can lead to chronic diseases. It is of important clinical and social significance to find effective appro...
Prediction of the anti-inflammatory effects of bioactive components of a Hippocampus species-based TCM formulation on chronic kidney disease using network pharmacology
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCHZhang, Lingyu Lu, Sitong Hu, Zhang Liao, Mingneng Li, Chengpeng Kong, Songzhi  出版年:2021
Purpose: To systematically study and predict the therapeutic targets and signaling pathways of Hippocampus (HPC) against chronic kidney disease (CKD) using network pharmacology. Methods: By combining database mining, lit...
Anti-Photoaging Effects of Nanocomposites of Amphiphilic Chitosan/18β-Glycyrrhetinic Acid
MOLECULESQuan, Weiyan Kong, Songzhi Li, Sidong Ouyang, Qianqian Lu, Sitong Guo, Jiaqi Wu, Kefeng Zhao, Wei Luo, Hui  出版年:2023
Improving the transdermal absorption of weakly soluble drugs for topical use can help to prevent and treat skin photoaging. Nanocrystals of 18 beta-glycyrrhetinic acid (i.e., NGAs) prepared by high-pressure homogenizatio...
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