GUT MICROBESPatil, Yadnyavalkya Gooneratne, Ravi Ju, Xiang-Hong 出版年：2020
It is well established that pig gut microbiota plays a critical role in maintaining metabolic homeostasis as well as in a myriad of physiological, neurological and immunological functions; including protection from patho...
The protective mechanism of chitosan oligosaccharide (COS) against lipopolysaccharides (LPS) -induced inflammatory responses in IPEC-J2 and in mice with DSS dextran sulfate sodium (DSS) -induced colitis is reported. Upon...
ENVIRONMENTAL TOXICOLOGYLiu, Han Nie, Fang-Hong Lin, Hong-Ying Ma, Yi Ju, Xiang-Hong Chen, Jin-Jun Gooneratne, Ravi 出版年：2016
3,3,4,4,5-Pentachlorobiphenyl (PCB126) cause multiple adverse effects in organisms including animals and humans. Although PCB toxicities are linked to oxidative damage in rodents, the mechanism in early life stages of ze...
Heat stressed pigs show typical characteristics of inflammatory bowel disease (IBD). However, little is known about the pathogenesis of heat stress (HS)-induced IBD in pigs. In this study, we determined the effects of HS...
ENVIRONMENTAL TOXICOLOGYLiu, Han Nie, Fang-Hong Lin, Hong-Ying Ma, Yi Ju, Xiang-Hong Chen, Jin-Jun Gooneratne, Ravi 出版年：2016
Dioxin-like PCB126 is a persistent organic pollutant that causes a range of syndromes including developmental toxicity. Dioxins have a high affinity for aryl hydrocarbon receptor (AhR) and induce cytochrome P4501A (CYP1A...
FRONTIERS IN NUTRITIONYong, Yanhong Fang, Biao Huang, Yingxin Li, Junyu Yu, Tianyue Wu, Lianyun Hu, Canying Liu, Xiaoxi Yu, Zhichao Ma, Xingbin Gooneratne, Ravi Li, Sidong Abd El-Aty, A. M. Ju, Xianghong 出版年：2022
Tea tree oil (TTO) exhibits a potent antioxidant, antibacterial, and anti-inflammatory activity and is commonly used in skincare products. However, it is not clear whether TTO can protect gut barrier damage in inflammato...
The pathological mechanisms of gastrointestinal disorders, including inflammatory bowel disease (IBD), in pigs are poorly understood. We report the induction of intestinal inflammation in heat-stressed (HS) pigs, fecal m...
FEMS MICROBIOLOGY ECOLOGYYang, Jing Wu, Jin'en Li, Yating Zhang, Yong'e Cho, William C. Ju, Xianghong van Schothorst, Evert M. Zheng, Yadong 出版年：2021
The gut microbiota plays an important role in human health. In modern life, with the improvement of living conditions, the intake of high-sugar and high-fat diets as well as the large-scale use of antibacterial drugs hav...
Background With evidence of warming climates, it is important to understand the effects of heat stress in farm animals in order to minimize production losses. Studying the changes in the brain proteome induced by heat st...
Echinococcosis is a parasitic disease caused by the metacestodes of Echinococcus spp. The disease has a long latent period and is largely underdiagnosed, partially because of the lack of effective early diagnostic approa...
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