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945 条 记 录,以下是 1-30

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Neurobiology of rodent self-grooming and its value for translational neuroSCIence
NATURE REVIEWS NEUROSCIENCEKalueff, Allan V. Stewart, Adam Michael Song, Cai Berridge, Kent C. Graybiel, Ann M. Fentress, John C.  出版年:2016
Self-grooming is a complex innate behaviour with an evolutionarily conserved sequencing pattern and is one of the most frequently performed behavioural activities in rodents. In this Review, we discuss the neurobiology o...
Optimization of process parameters for supercritical carbon dioxide extraction of Passiflora seed oil by response surface methodology
JOURNAL OF SUPERCRITICAL FLUIDSLiu, Shucheng Yang, Feng Zhang, Chaohua Ji, Hongwu Hong, Pengzhi Deng, Chujin  出版年:2009
Response surface methodology (RSM) was employed to optimize the process parameters of supercritical carbon dioxide extraction of the passion fruit seed oil. The effects of temperature, pressure and extraction time on the...
Molecular psychiatry of zebrafish
MOLECULAR PSYCHIATRYStewart, A. M. Ullmann, J. F. P. Norton, W. H. J. Parker, M. O. Brennan, C. H. Gerlai, R. Kalueff, A. V.  出版年:2015
Due to their well-characterized neural development and high genetic homology to mammals, zebrafish (Danio rerio) have emerged as a powerful model organism in the field of biological psychiatry. Here, we discuss the molec...
In situ surface-enhanced Raman spectroscopy for detecting microplastics and nanoplastics in aquatic environments
SCIENCE OF THE TOTAL ENVIRONMENTLv, Lulu He, Lei Jiang, Shiqi Chen, Jinjun Zhou, Chunxia Qu, Junhao Lu, Yuqin Hong, Pengzhi Sun, Shengli Li, Chengyong  出版年:2020
The detection of microplastics and nanoplastics in the environment, especially plastic particles in aquatic environments in situ, still faces challenges due to the limitations of current methods, instruments and size of ...
Comparative Analyses of Zebrafish Anxiety-Like Behavior Using Conflict-Based Novelty Tests
ZEBRAFISHKysil, Elana V. Meshalkina, Darya A. Frick, Erin E. Echevarria, David J. Rosemberg, Denis B. Maximino, Caio Lima, Monica Gomes Abreu, Murilo S. Giacomini, Ana C. Barcellos, Leonardo J. G. Song, Cai Kalueff, Allan V.  出版年:2017
Modeling of stress and anxiety in adult zebrafish (Danio rerio) is increasingly utilized in neuroSCIence research and central nervous system (CNS) drug discovery. Representing the most commonly used zebrafish anxiety mod...
Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction
CELL RESEARCHLi, Zhong Brecher, Matthew Deng, Yong-Qiang Zhang, Jing Sakamuru, Srilatha Liu, Binbin Huang, Ruili Koetzner, Cheri A. Allen, Christina A. Jones, Susan A. Chen, Haiying Zhang, Na-Na Tian, Min Gao, Fengshan Lin, Qishan Banavali, Nilesh Zhou, Jia Boles, Nathan Xia, Menghang Kramer, Laura D. Qin, Cheng-Feng Li, Hongmin  出版年:2017
Recent outbreaks of Zika virus (ZIKV) highlight an urgent need for therapeutics. The protease complex NS2B-NS3 plays essential roles during flaviviral polyprotein processing, and thus represents an attractive drug target...
The role of omega-3 polyunsaturated fatty acids eicosapentaenoic and docosahexaenoic acids in the treatment of major depression and Alzheimer's disease: Acting separately or synergistically?
PROGRESS IN LIPID RESEARCHSong, Cai Shieh, Chu-Hsin Wu, Yi-Shyuan Kalueff, Allan Gailcvvad, Siddharth Su, Kuan-Pin  出版年:2016
Omega-3 polyunsaturated fatty acids (n-3-PUFAs), mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), may improve or prevent some psychiatric and neurodegenerative diseases in both experimental and clinical...
Marine Collagen Peptides from the Skin of Nile Tilapia (Oreochromis niloticus): Characterization and Wound Healing Evaluation
MARINE DRUGSHu, Zhang Yang, Ping Zhou, Chunxia Li, Sidong Hong, Pengzhi  出版年:2017
Burns can cause tremendous economic problems associated with irreparable harm to patients and their families. To characterize marine collagen peptides (MCPs) from the skin of Nile tilapia (Oreochromis niloticus), molecul...
Zebrafish models in neuropsychopharmacology and CNS drug discovery
BRITISH JOURNAL OF PHARMACOLOGYKhan, Kanza M. Collier, Adam D. Meshalkina, Darya A. Kysil, Elana V. Khatsko, Sergey L. Kolesnikova, Tatyana Morzherin, Yury Yu Warnick, Jason E. Kalueff, Allan V. Echevarria, David J.  出版年:2017
Despite the high prevalence of neuropsychiatric disorders, their aetiology and molecular mechanisms remain poorly understood. The zebrafish (Danio rerio) is increasingly utilized as a powerful animal model in neuropharma...
A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease
PLOS PATHOGENSBrecher, Matthew Li, Zhong Liu, Binbin Zhang, Jing Koetzner, Cheri A. Alifarag, Adham Jones, Susan A. Lin, Qishan Kramer, Laura D. Li, Hongmin  出版年:2017
The flavivirus genome encodes a single polyprotein precursor requiring multiple cleavages by host and viral proteases in order to produce the individual proteins that constitute an infectious virion. Previous studies hav...
Enhanced flavonoid production in hairy root cultures of Glycyrrhiza uralensis Fisch by combining the over-expression of chalcone isomerase gene with the elicitation treatment
PLANT CELL REPORTSZhang, Hai-Chao Liu, Jing-Mei Lu, Hong-Yu Gao, Shan-Lin  出版年:2009
Economically important compounds, such as licorice flavonoids, are present in insufficient amounts in the hairy roots. To overcome this problem, we took the transgenic approach combined with the elicitation technique to ...
Thermogravimetric analysis of chitosan
JOURNAL OF APPLIED POLYMER SCIENCEHong, Peng-Zhi Li, Si-Dong Ou, Chun-Yan Li, Cheng-Peng Yang, Lei Zhang, Chao-Hua  出版年:2007
The thermal degradation of chitosan at different heating rates B in nitrogen was studied by thermogravimetric analysis. The results indicate that the thermal degradation of chitosan in nitrogen is a one-step reaction. Th...
Minocycline ameliorates depressive behaviors and neuro-immune dysfunction induced by chronic unpredictable mild stress in the rat
BEHAVIOURAL BRAIN RESEARCHZhang, Cai Zhang, Yong-Ping Li, Yu-Yu Liu, Bai-Ping Wang, Hao-Yin Li, Kang-Wei Zhao, Shannon Song, Cai  出版年:2019
Activated microglia-induced neuroinflammation can stimulate the hypothalamic-pituitary-adrenal (HPA) axis to release glucocorticoids and suppress astrocyte functions, such as reducing neurotrophin production, which occur...
Absorption, metabolism and bioavailability of flavonoids: a review
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITIONChen, Lei Cao, Hui Huang, Qun Xiao, Jianbo Teng, Hui  出版年:0
Flavonoids are stored in various plants and widely presented in different kinds of food in variable amounts. Plant roots, stems, leaves, flowers and fruits are known to have high amounts of flavonoids. However, flavonoid...
Zebrafish neurobehavioral phenomics for aquatic neuropharmacology and toxicology research
AQUATIC TOXICOLOGYKalueff, Allan V. Echevarria, David J. Homechaudhuri, Sumit Stewart, Adam Michael Collier, Adam D. Kaluyeva, Aleksandra A. Li, Shaomin Liu, Yingcong Chen, Peirong Wang, JiaJia Yang, Lei Mitra, Anisa Pal, Subharthi Chaudhuri, Adwitiya Roy, Anwesha Biswas, Missidona Roy, Dola Podder, Anupam Poudel, Manoj K. Katare, Deepshikha P. Mani, Ruchi J. Kyzar, Evan J. Gaikwad, Siddharth Michael Nguyen Song, Cai  出版年:2016
Zebrafish (Danio rerio) are rapidly emerging as an important model organism for aquatic neuropharmacology and toxicology research. The behavioral/phenotypic complexity of zebrafish allows for thorough dissection of compl...
Recent advances in enzyme immobilization based on novel porous framework materials and its applications in biosensing
COORDINATION CHEMISTRY REVIEWSFeng, Yanmei Xu, Ying Liu, Shucheng Wu, Di Su, Zhuoqun Chen, Guang Liu, Jianghua Li, Guoliang  出版年:2022
Enzyme immobilization in nano-space to maintain or even enhance their activity and stability is generally challenging. In recent years, metal-organic frameworks (MOFs), covalent organic frameworks (COFs) and hydrogen-bon...
A simple method for detecting and quantifying microplastics utilizing fluorescent dyes - Safranine T, fluorescein isophosphate, Nile red based on thermal expansion and contraction property
ENVIRONMENTAL POLLUTIONLv, Lulu Qu, Junhao Yu, Zihua Chen, Daihuan Zhou, Chunxia Hong, Pengzhi Sun, Shengli Li, Chengyong  出版年:2019
Microplastics (particle size <5 mm) are an emerging contaminant for aquatic environmental, which have attracted increasing attention in worldwide range. In this study, an improved fluorescent staining method for detectio...
Psychosocial stress on neuroinflammation and cognitive dysfunctions in Alzheimer's disease: the emerging role for microglia?
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWSPiirainen, Sami Youssef, Andrew Song, Cai Kalueff, Allan V. Landreth, Gary E. Malm, Tarja Tian, Li  出版年:2017
Chronic psychosocial stress is increasingly recognized as a risk factor for late-onset Alzheimer's disease (LOAD) and associated cognitive deficits. Chronic stress also primes microglia and induces inflammatory responses...
Concentration of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) of tuna oil by urea complexation: optimization of process parameters
JOURNAL OF FOOD ENGINEERINGLiu, Shucheng Zhang, Chaohua Hong, Pengzhi Ji, Hongwu  出版年:2006
Production of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) concentrates from tuna oil was optimized. In the process, the liquid recovery yield (Y-1) and the total content of DHA and EPA (Y-2) were response ...
EPA is More Effective than DHA to Improve Depression-Like Behavior, Glia Cell Dysfunction and Hippcampal Apoptosis Signaling in a Chronic Stress-Induced Rat Model of Depression
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESPeng, Zhilan Zhang, Cai Yan, Ling Zhang, Yongping Yang, Zhiyou Wang, Jiajia Song, Cai  出版年:2020
Clinical evidence indicated that eicosapentaenoic acid (EPA) was more effective than docosahexaenoic acid (DHA) in depression treatment. However, possible mechanisms remain unclear. Here, a chronic unpredictable mild str...
Effect of vacuum impregnation of red sea bream (Pagrosomus major) with herring AFP combined with CS@Fe3O4 nanoparticles during freeze-thaw cycles
FOOD CHEMISTRYNian, Linyu Cao, Ailing Cai, Luyun Ji, Hongwu Liu, Shucheng  出版年:2019
This study examined the effect of herring antifreeze protein (hAFP) combined with chitosan magnetic nanoparticles (CS@Fe3O4), applied through vacuum impregnation, on protein conformation and moisture state of red sea bre...
Chemotaxis-selective colonization of mangrove rhizosphere microbes on nine different microplastics
SCIENCE OF THE TOTAL ENVIRONMENTXie, Huifeng Chen, Jinjun Feng, Limin He, Lei Zhou, Chunxia Hong, Pengzhi Sun, Shengli Zhao, Hui Liang, Yanqiu Ren, Lei Zhang, Yueqin Li, Chengyong  出版年:2021
Microplastics pollution poses a new threat to the environment of intertidal zone. The sea forest, mangrove, has been polluted by a large number of plastic debris worldwide. To fill the gaps in knowledge of mangrove rhizo...
Isolation and characterisation of acid-solubilised collagen from the skin of Nile tilapia (Oreochromis niloticus)
FOOD CHEMISTRYZeng, Shao-kui Zhang, Chao-hua Lin, Hong Yang, Ping Hong, Peng-zhi Jiang, Zhihong  出版年:2009
Acid-solubilised collagen (ASC) was extracted from the skin of Nile tilapia (Oreochromis niloticus) and characterisation was studied. The results indicated that the yield of ASC was 39.4% on the basis of dry weight. This...
Thermal degradation kinetics of chitosan-cobalt complex as studied by thermogravimetric analysis
CARBOHYDRATE POLYMERSOu, Chun-Yan Zhang, Chao-Hua Li, Si-Dong Yang, Lei Dong, Jing-Jing Mo, Xue-Liu Zeng, Mu-Ting  出版年:2010
The thermal degradation of chitosan-cobalt complex at different heating rates in nitrogen was studied by thermogravimetric analysis (TGA) in the temperature range 30-800 degrees C. Fourier transform-infrared (FTIR) and X...
Response surface methodology for autolysis parameters optimization of shrimp head and amino acids released during autolysis
FOOD CHEMISTRYCao, Wenhong Zhang, Chaohua Hong, Pengzhi Ji, Hongwu  出版年:2008
Protein hydrolysates were prepared from the head waste of Penaens vannamei, a China seawater major shrimp by autolysis method. Autolysis conditions (viz., temperature, pH and substrate concentration) for preparing protei...
Effect of kappa-carrageenan on gelation and gel characteristics of Antarctic krill (Euphausia superba) protein isolated with isoelectric solubilization/precipitation
FOOD CHEMISTRYZheng, Huina Beamer, Sarah K. Matak, Kristen E. Jaczynski, Jacek  出版年:2019
Isoelectric solubilization/precipitation (ISP) was used to extract krill protein isolate (KPI). Due to krill endogenous proteases ISP-KPI barely forms gel which is a major hurdle in wide application of this tremendous pr...
Bioactive compounds, health benefits, and industrial applications of Tartary buckwheat (Fagopyrum tataricum)
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITIONZou, Liang Wu, Dingtao Ren, Guixing Hu, Yichen Peng, Lianxin Zhao, Jianglin Garcia-Perez, Pascual Carpena, Maria Prieto, Miguel A. Cao, Hui Cheng, Ka-Wing Wang, Mingfu Simal-Gandara, Jesus John, Oliver D. Rengasamy, Kannan R. R. Zhao, Gang Xiao, Jianbo  出版年:0
Tartary buckwheat belongs to the family Polygonaceae, which is a traditionally edible and medicinal plant. Due to its various bioactive compounds, the consumption of Tartary buckwheat is correlated to a wide range of hea...
Toxic Effects on Bioaccumulation, Hematological Parameters, Oxidative Stress, Immune Responses and Tissue Structure in Fish Exposed to Ammonia Nitrogen: A Review
ANIMALSXu, Zhenkun Cao, Jie Qin, Xiaoming Qiu, Weiqiang Mei, Jun Xie, Jing  出版年:2021
Simple Summary: Ammonia nitrogen is a common environmental limiting factor in aquaculture, which can accumulate rapidly in water and reach toxic concentrations. In most aquatic environments, fish are vulnerable to the to...
Combined Enzymatic and Mechanical Cell Disruption and Lipid Extraction of Green Alga Neochloris oleoabundans
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESWang, Dongqin Li, Yanqun Hu, Xueqiong Su, Weimin Zhong, Min  出版年:2015
Microalgal biodiesel is one of the most promising renewable fuels. The wet technique for lipids extraction has advantages over the dry method, such as energy-saving and shorter procedure. The cell disruption is a key fac...
A neutral polysaccharide with a triple helix structure from ginger: Characterization and immunomodulatory activity
FOOD CHEMISTRYYang, Xiaolong Wei, Siqing Lu, Xiaoming Qiao, Xuguang Simal-Gandara, Jesus Capanoglu, Esra Wozniak, Lukasz Zou, Liang Cao, Hui Xiao, Jianbo Tang, Xiaozhen Li, Ningyang  出版年:2021
A neutral ginger polysaccharide fraction (NGP) was isolated from ginger, and its primary structures and immunomodulatory activity were investigated. The results showed that NGP had a low molecular weight of 6305 Da. NGP ...
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