Chitosan oligosaccharide (COS), a natural polysaccharide with good antioxidant and anti-inflammatory properties, is the depolymerized product of chitosan possessing various biological activities. The present study was de...
Skin photoaging (SP) is a premature skin-aging damage after repeated exposure to ultraviolet (UV) radiation, mainly characterized by oxidative stress and inflammatory disequilibrium, which makes skin show the typical sym...
Hemorrhea is one of the major problems in war, trauma care, and surgical operation that threaten the life of the injured and patients. As a novel polymeric hemostatic agent, biodegradable chitosan can stop bleeding throu...
Our earlier research indicated that chitosan-gentamicin conjugate (CS-GT) possesses superior antimicrobial activity and good water solubility. To develop CS-GT-based scald dressings, the antibacterial properties of CS-GT...
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESOuyang Qianqian Kong Songzhi Huang Yongmei Ju Xianghong Li Sidong Li Puwang Luo Hui 出版年：2021
There is an urgent need for wound dressings to treat partial-thickness burns. Hydrogels are a promising material that can maintain hydration to promote necrotic tissue removal. Tilapia peptides (TP) and hydroxyapatite (H...
We wished to investigate the role of a tilapia skin collagen polypeptide (TSCP; molecular weight < 3 kDa) in alleviating liver and kidney injuries in aging mice induced by D-galactose (D-gal) and its underlying mechanism...
A new type of wound healing agent was developed using two marine biomaterials (squid ink polysaccharide and chitosan) as carriers and calcium chloride as an initiator for coagulation. Based on central composite design re...
When the aquaculture water environment deteriorates or the temperature rises, shrimp are susceptible to viral or bacterial infections, causing a large number of deaths. This study comprehensively evaluated the effects of...
Long-term excessive alcohol intake can easily lead to gastritis, gastric ulcer, and gastric bleeding. In this paper, the gastric acid-responsive hydrogel of CS-NAC/alginate/tilapia collagen peptide (CS-NAC/ALG/TCP) was d...
18 beta-Glycyrrhetinic acid (GA) is often topically applied in clinical treatment of inflammatory skin diseases. However, GA has poor solubility in water, which results in poor skin permeability and low bioavailability. ...
Chitosan is the only cationic polysaccharide found in nature. It has broad application prospects in biomaterials, but its application is limited due to its poor solubility in water. A novel chitosan derivative was synthe...
Purpose: To systematically study and predict the therapeutic targets and signaling pathways of Hippocampus (HPC) against chronic kidney disease (CKD) using network pharmacology. Methods: By combining database mining, lit...
FOOD SCIENCE AND TECHNOLOGY RESEARCHKong, Song-Zhi Lin, Guo-Sheng Liu, Jing-Jing Su, Ling-Ye Zeng, Lei Luo, Dan-Dan Su, Zi-Ren Wang, Hong-Feng 出版年：2018
The aim of this study was to investigate the hepatoprotective effect of ultrafine powder of Dendrobium officinale (UDO) against acetaminophen (APAP)-induced liver injury in mice. ICR mice were orally administered with UD...
Long-term alcohol intake or drinking large quantities of alcohol at one time can cause organ damage, which in turn can lead to chronic diseases. It is of important clinical and social significance to find effective appro...
DRUG DESIGN DEVELOPMENT AND THERAPYKong, Songzhi Lv, Lijiao Guo, Jiaqi Yang, Xiaohong Liao, Mingneng Zhao, Tianyang Sun, Haiyang Zhang, Shuqun Li, Wenjie 出版年：2023
Background: Photoaging decreases quality of life and increases the risk of skin cancer, underscoring the urgent need to explore natural, high-efficacy, anti-skin photoaging (SP) active substances. Methods: In this study,...
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