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鲁义善，博士，教授，博士生导师/硕士生导师。广东省“千百十”工程省级培养对象，深圳市地方级领军人才，全国首席科学传播专家，国际食品法典（CAC）抗菌素耐药专家委员会委员，全国水产品质量安全专家工作组成员，农业部水产养殖病害防治专家委员会委员，全国兽药残留与耐药性控制专家委员，挪威特罗姆瑟大学渔业科学学院访问学者。现为广东省水生动物健康评估工程技术研究中心主任，广东省教育厅 “广东海洋大学-英国斯特灵大学渔用疫苗实用化技术”国际合作平台负责人，深圳市海水经济动物种苗健康评价公共技术服务平台主任。近年来主持国家自然科学基金2项、省部级项目7项；参与9...   详细>>

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共 375 条 记 录，以下是 1-30

A review on the application of <i>Bacillus</i> as probiotics in aquaculture
FISH & SHELLFISH IMMUNOLOGYKuebutornye, Felix K. A. Abarike, Emmanuel Delwin Lu, Yishan  出版年：2019
Probiotics use in aquaculture has gained attention as microbial candidates to maintain the health and the wellbeing of many aquaculture animals. Among the many microbial candidates, probiotic Bacillus has sporulation cap...
Effects of a commercial probiotic BS containing <i>Bacillus subtilis</i> and <i>Bacillus licheniformis</i> on growth, immune response and disease resistance in Nile tilapia, <i>Oreochromis niloticus</i>
FISH & SHELLFISH IMMUNOLOGYAbarike, Emmanuel Delwin Cai, Jia Lu, Yishan Yu, Huang Chen, Lihua Jian, Jichang Tang, Jufen Jun, Liang Kuebutornye, Felix K. A.  出版年：2018
The present study evaluated a commercial probiotic designated as BS (a mix of B. subtilis and B. licheniformis) to ascertain its efficacy and the dose necessary to improve growth, immune response, and disease resistance ...
The use of <i>Bacillus</i> species in maintenance of water quality in aquaculture: A review
AQUACULTURE REPORTSHlordzi, Vivian Kuebutornye, Felix K. A. Afriyie, Gyamfua Abarike, Emmanuel Delwin Lu, Yishan Chi, Shuyan Anokyewaa, Melody A.  出版年：2020
Aquaculture effluent is often associated with increased organic carbon, suspended solids, phosphates, nitrogenous species (nitrates, nitrites, and ammonia), chemical oxygen demand and biological oxygen demand. This is re...
Mechanisms and the role of probiotic <i>Bacillus</i> in mitigating fish pathogens in aquaculture
FISH PHYSIOLOGY AND BIOCHEMISTRYKuebutornye, Felix K. A. Abarike, Emmanuel Delwin Lu, Yishan Hlordzi, Vivian Sakyi, Michael Essien Afriyie, Gyamfua Wang, Zhiwen Li, Yuan Xie, Cai Xia  出版年：2020
Diseases are natural components of the environment, and many have economic implications for aquaculture and fisheries. Aquaculture is a fast-growing industry with the aim to meet the high protein demand of the ever-incre...
Fish gut-liver immunity during homeostasis or inflammation revealed by integrative transcriptome and proteome studies
SCIENTIFIC REPORTSWu, Nan Song, Yu-Long Wang, Bei Zhang, Xiang-Yang Zhang, Xu-Jie Wang, Ya-Li Cheng, Ying-Yin Chen, Dan-Dan Xia, Xiao-Qin Lu, Yi-Shan Zhang, Yong-An  出版年：2016
The gut-associated lymphoid tissue, connected with liver via bile and blood, constructs a local immune environment of both defense and tolerance. The gut-liver immunity has been well-studied in mammals, yet in fish remai...
Effects of three host-associated <i>Bacillus</i> species on mucosal immunity and gut health of Nile tilapia, <i>Oreochromis</i> <i>niloticus</i> and its resistance against <i>Aeromonas hydrophila</i> infection
FISH & SHELLFISH IMMUNOLOGYKuebutornye, Felix K. A. Wang, Zhiwen Lu, Yishan Abarike, Emmanuel Delwin Sakyi, Michael Essien Li, Yuan Xie, Cai Xia Hlordzi, Vivian  出版年：2020
Skin and intestinal mucosa lymphoid tissues are known to be the fish's first line of defence since they serve as the first point of contact for pathogens. Only few studies have investigated the influence of host-associat...
Complete Genome Sequence of <i>Streptococcus agalactiae</i> ZQ0910, a Pathogen Causing Meningoencephalitis in the GIFT Strain of Nile Tilapia (<i>Oreochromis niloticus</i>)
JOURNAL OF BACTERIOLOGYWang, Bei Jian, Jichang Lu, Yishan Cai, Shuanghu Huang, Yuchong Tang, Jufen Wu, Zaohe  出版年：2012
Streptococcus agalactiae (group B streptococcus [GBS]) is a pathogen that causes meningoencephalitis in Nile tilapia (Oreochromis niloticus). Here, we reported the complete genome sequence of S. agalactiae strain ZQ0910,...
CHARACTERIZATION OF PATHOGENIC <i>AEROMONAS VERONII</i> BV. <i>VERONII</i> ASSOCIATED WITH ULCERATIVE SYNDROME FROM CHINESE LONGSNOUT CATFISH (<i>LEIOCASSIS</i> <i>LONGIROSTRIS</i> GUNTHER)
BRAZILIAN JOURNAL OF MICROBIOLOGYCai, Shuang-Hu Wu, Zao-He Jian, Ji-Chang Lu, Yi-Shan Tang, Ju-Feng  出版年：2012
273 bacterial strains were isolated from 20 Chinese longsnout catfish samples. The biochemical characteristics of all strains conformed to the species description of Aeromonas veronii bv. veronii on the basis of Vitek GN...
Comprehensive identification and profiling of Nile tilapia (<i>Oreochromis niloticus</i>) microRNAs response to <i>Streptococcus agalactiae</i> infection through high-throughput sequencing
FISH & SHELLFISH IMMUNOLOGYWang, Bei Gan, Zhen Cai, Shuanghu Wang, Zhongliang Yu, Dapeng Lin, Ziwei Lu, Yishan Wu, Zaohe Jian, Jichang  出版年：2016
MicroRNAs are a kind of small non-coding RNAs that participate in various biological processes. Deregulated microRNA expression is associated with several types of diseases. Tilapia (Oreochromis niloticus) is an importan...
Cloning and expression of heat shock protein 70 gene in the haemocytes of pearl oyster (<i>Pinctada</i> <i>fucata</i>, Gould 1850) responding to bacterial challenge
FISH & SHELLFISH IMMUNOLOGYWang, Zhongliang Wu, Zaohe Jian, Jichang Lu, Yishan  出版年：2009
The cDNA of pearl oyster Pinctada fucata Hsp70 (designated PFHsp70) was cloned by EST and rapid amplification of cDNA ends (RACE) techniques. The full length of PFHsp70 cDNA was 2376 bp, consisting of a 5'-terminal untra...
Immunostimulatory effects of artificial feed supplemented with a Chinese herbal mixture on <i>Oreochromis niloticus</i> against <i>Aeromonas hydrophila</i>
FISH & SHELLFISH IMMUNOLOGYTang, Jufen Cai, Jia Liu, Ran Wang, Jiamin Lu, Yishan Wu, Zaohe Jian, Jichang  出版年：2014
The effects of a Chinese herbal mixture (CHM) composed of astragalus, angelica, hawthorn, Licorice root and honeysuckle on immune responses and disease resistant of Nile tilapia (Oreochromis niloticus GIFT strain) were i...
Transcriptome analysis of immune-related gene expression in hybrid snakehead (<i>Channa maculata</i> ♀ x <i>Channa argus</i> ♂) after challenge with <i>Nocardia seriolae</i>
FISH & SHELLFISH IMMUNOLOGYChen, Jianlin Li, Yanqun Wang, Wenji Xia, Liqun Wang, Zhiwen Hou, Suying Huang, Jiahui Lu, Yishan  出版年：2018
Hybrid snakehead fish (Channa maculata female x Channa cups male), a new species used in freshwater aquaculture in China, is the common host of an epizootic bacterial infection by Nocardia seriolae. However, the informat...
In vivo assessment of the probiotic potentials of three host -associated Bacillus species on growth performance, health status and disease resistance of Oreochromis niloticus against Streptococcus agalactiae
AQUACULTUREKuebutornye, Felix K. A. Tang, Jufen Cai, Jia Yu, Huang Wang, Zhiwen Abarike, Emmanuel Delwin Lu, Yishan Li, Yuan Afriyie, Gyamfua  出版年：2020
Four weeks feeding trial was conducted to assess the in vivo probiotic potentials of three host-associated Bacillus species in O. niloticus. The fish were divided into five treatment groups and fed with diets containing ...
Single-cell RNA-seq reveals different subsets of non-specific cytotoxic cells in teleost
GENOMICSNiu, Jinzhong Huang, Yu Liu, Xinchao Zhang, Zhiqiang Tang, Jufen Wang, Bei Lu, Yishan Cai, Jia Jian, Jichang  出版年：2020
Non-specific cytotoxic cells (Ncc) are important cytotoxic leukocytes in teleost immune system. However, the Ncc subsets have not been clarified. Thus, we create a comprehensive cell map of similar to 24,062 head kidney-...
NK-lysin from <i>Oreochromis niloticus</i> improves antimicrobial defence against bacterial pathogens
FISH & SHELLFISH IMMUNOLOGYHuang, Yu Zheng, Qi Niu, Jinzhong Tang, Jufen Wang, Bei Abarike, Emmanuel Delwin Lu, Yishan Cai, Jia Jian, Jichang  出版年：2018
NK-lysin, an effector of cytotoxic T cells and natural killer cells, is a potent antimicrobial peptide widely distributed in mammals. Homologues of NK-lysin have been discovered in several teleost species, but only sever...
In vitro Assessment of the Probiotic Characteristics of Three <i>Bacillus</i> Species from the Gut of Nile Tilapia, <i>Oreochromis niloticus</i>
PROBIOTICS AND ANTIMICROBIAL PROTEINSKuebutornye, Felix K. A. Lu, Yishan Abarike, Emmanuel Delwin Wang, Zhiwen Li, Yuan Sakyi, Michael Essien  出版年：2020
Probiotics used in aquaculture are mostly from non-fish sources, as a result ineffective in eliciting the desired effects in aquatic animals. In this study, threeBacillusspecies were isolated from the digestive tract of ...
Molecular characterization and expression of CD2BP2 in Nile tilapia (<i>Oreochromis niloticus</i>) in response to <i>Streptococcus agalactiae</i> stimulus
GENEGan, Zhen Wang, Bei Lu, Yishan Cai, Shuanghu Cai, Jia Jian, JiChang Wu, Zaohe  出版年：2014
CD2BP2 (CD2 cytoplasmic tail binding protein 2), one of several proteins interacting with the cytoplasmic tail of CD2, plays a crucial role in CD2-triggered T cell activation and nuclear splicing. The studies on CD2BP2 h...
Transcriptome analysis of the pearl oyster (<i>Pinctada fucata</i>) hemocytes in response to <i>Vibrio alginolyticus</i> infection
GENEWang, Zhongliang Wang, Bei Chen, Gang Jian, Jichang Lu, Yishan Xu, Youhou Wu, Zaohe  出版年：2016
The pearl oyster Pinctada fucata is cultured widely for production of marine pearls in China, while mass mortalities, likely related to pathogenic infections, have occurred frequently in juvenile, mother and operated oys...
Lactic acid bacteria, <i>Enterococcus faecalis</i> Y17 and <i>Pediococcus pentosaceus</i> G11, improved growth performance, and immunity of mud crab (<i>Scylla paramamosain</i>)
FISH & SHELLFISH IMMUNOLOGYYang, Qiuhua Lu, Yongling Zhang, Ming Gong, Yi Li, Zhongzhen Ngoc Tuan Tran He, Yuyong Zhu, Chunhua Lu, Yishan Zhang, Yueling Li, Shengkang  出版年：2019
Mud crabs (Scylla paramamosain), a commercially important cultured species in the southeastern region of China, is usually infected by Vibriosis or parasites, causing great economic losses in cultured farms. Previous stu...
Conservation of structural and interactional features of CD28 and CD80/86 molecules from Nile tilapia (<i>Oreochromis niloticus</i>)
FISH & SHELLFISH IMMUNOLOGYHuang, Yu Wang, Zhiwen Zheng, Qi Tang, Jufen Cai, Jia Lu, Yishan Jian, Jichang  出版年：2018
Interaction of CD28 with CD80 or CD86 molecules provides a costimulatory signals required in T cell activation. In this study, we cloned and analyzed a CD28 gene (On-CD28) and a CD80/86 gene (On-CD80/86) from Nile tilapi...
Molecular and functional characterization of CD59 from Nile tilapia (<i>Oreochromis niloticus</i>) involved in the immune response to <i>Streptococcus agalactiae</i>
FISH & SHELLFISH IMMUNOLOGYGan, Zhen Wang, Bei Zhou, Wei Lu, Yishan Zhu, Weiwei Tang, Jufen Jan, JiChang Wu, Zaohe  出版年：2015
CD59, the major inhibitor of membrane attack complex, plays a crucial role in regulation of complement activation. In this paper, a CD59 gene of Nile tilapia, Oreochromis niloticus (designated as On-CD59) was cloned and ...
Modulation of nutrient utilization, growth, and immunity of Nile tilapia, <i>Oreochromis niloticus</i>: the role of probiotics
AQUACULTURE INTERNATIONALKuebutornye, Felix K. A. Abarike, Emmanuel Delwin Sakyi, Michael Essien Lu, Yishan Wang, Zhiwen  出版年：2020
The production of Nile tilapia, Oreochromis niloticus, over the last few years has increased due to the adoption of intensive farming technologies. However, the continuous increase in O. niloticus production must be base...
Loop-mediated isothermal amplification method for rapid detection of <i>Vibrio alginolyticus</i>, the causative agent of vibriosis in mariculture fish
LETTERS IN APPLIED MICROBIOLOGYCai, S. H. Lu, Y. S. Wu, Z. -H. Jian, J. C. Wang, B. Huang, Y. C.  出版年：2010
Aims: The purpose of this study was to develop a loop-mediated isothermal amplification (LAMP) method for the rapid, sensitive and simple detection of Vibrio alginolyticus in mariculture fish. Methods and Results: LAMP p...
Fish Galectin8-Like Exerts Positive Regulation on Immune Response Against Bacterial Infection
FRONTIERS IN IMMUNOLOGYNiu, Jinzhong Huang, Yu Liu, Xinchao Wu, Fenglei Tang, Jufen Wang, Bei Lu, Yishan Cai, Jia Jian, Jichang  出版年：2020
Galectin-8 is a member of the galectin family that is involved in immune response against pathogens. However, the roles of fish galectin-8 during pathogen infection require comprehensive studies. In this study, a galecti...
A tandem-repeat galectin involved in innate immune response of the pearl oyster <i>Pinctada fucata</i>
MARINE GENOMICSWang, Zhongliang Jian, Jichang Lu, Yishan Wang, Bei Wu, Zaohe  出版年：2011
The cDNA of a tandem-repeat galectin from the pearl oyster Pinctada fucata (designated PfGal) was cloned by expressed sequence tag (EST) and rapid amplification of cDNA ends (RACE) techniques. The full-length cDNA of PfG...
Development of DNA vaccines encoding ribosomal proteins (RplL and RpsA) against <i>Nocardia seriolae</i> infection in fish
FISH & SHELLFISH IMMUNOLOGYChen, Jianlin Chen, Zhenwei Wang, Wenji Hou, Suying Cai, Jia Xia, Liqun Lu, Yishan  出版年：2020
Nocardia seriolae, a Gram-positive pathogen, has been identified as the causative agent of fish nocardiosis. DNA vaccination has been proven to be effective in conferring protection against bacterial infection in fish. T...
<i>Mitf</i> Involved in Innate Immunity by Activating Tyrosinase-Mediated Melanin Synthesis in <i>Pteria penguin</i>
FRONTIERS IN IMMUNOLOGYYu, Feifei Lu, Yishan Zhong, Zhiming Qu, Bingliang Wang, Meifang Yu, Xiangyong Chen, Jiayu  出版年：2021
The microphthalmia-associated transcription factor (MITF) is an important transcription factor that plays a key role in melanogenesis, cell proliferation, survival and immune defense in vertebrate. However, its function ...
卵形鲳鲹结节病病原的分离与鉴定
《广东海洋大学学报》黄郁葱 简纪常 吴灶和 鲁义善 余坦健  出版年：2008
从湛江港、阳江闸坡海水网箱养殖的患结节病卵形鲳鲹(Trachinotus ovatus)中分离一株细菌,回归感染结果证明该菌是引起卵形鲳鲹结节病的病原,对卵形鲳鲹半致死浓度为45 g-1。该菌株呈革兰阳性,好氧,具有弱抗...
关键词：卵形鲳鲹  结节病  诺卡氏菌  16S  rDNA  被引量：33
A comprehensive profile of the tilapia (<i>Oreochromis niloticus</i>) circular RNA and circRNA-miRNA network in the pathogenesis of meningoencephalitis of teleosts
MOLECULAR OMICSFan, Bolin Chen, Funuan Li, Yuan Wang, Zhongliang Wang, Zhiwen Lu, Yishan Wu, Zaohe Jian, Jichang Wang, Bei  出版年：2019
The pathogenesis of tilapia meningoencephalitis is still unclear, where the involvement of circRNA is considered for its active role as a `` miRNA sponge''. Therefore, we aimed to investigate the profile of circRNA in ti...
Molecular and functional characterization of peptidoglycan-recognition protein SC2 (PGRP-SC2) from Nile tilapia (<i>Oreochromis niloticus</i>) involved in the immune response to <i>Streptococcus agalactiae</i>
FISH & SHELLFISH IMMUNOLOGYGan, Zhen Chen, Shannan Hou, Jing Huo, Huijun Zhang, Xiaolin Ruan, Baiye Laghari, Zubair Ahmed Li, Li Lu, Yishan Nie, Pin  出版年：2016
PGRP-SC2, the member of PGRP family, plays an important role in regulation of innate immune response. In this paper, a PGRP-SC2 gene of Nile tilapia, Oreochromis niloticus (designated as On-PGRP-SC2) was cloned and its e...
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