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李思东，广东海洋大学理学院院长、应用化学系教授。享受国务院政府特殊津贴；国家自然科学基金项目和国家863项目评审专家,；农业部热带作物产品加工重点开放实验室学术委员会委员。国际专业杂志POLYMER、 JOURNAL OF APPLIED POLYMER SCIENCE和JOURNAL OF MASS SPECTROMETRY等杂志的审稿专家。 ... 详细>>

被引量：1,733H指数：25SCI-EXPANDED: 48EI: 27北大核心: 16CSCD: 14

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共 103 条记录，以下是 1-30

Chitosan-Based Composite Materials for Prospective Hemostatic Applications: MARINE DRUGSHu, Zhang Zhang, Dong-Ying Lu, Si-Tong Li, Pu-Wang Li, Si-Dong 出版年：2018; Effective hemostasis is vital to reduce the pain and mortality of patients, and the research and development of hemostatic materials are prerequisite for effective hemostasis. Chitosan (CS), with good biodegradability, b...

Preparation and evaluation of chitosan/alginate porous microspheres/Bletilla striata polysaccharide composite hemostatic sponges: CARBOHYDRATE POLYMERSWang, Chao Luo, Wenfeng Li, Puwang Li, Sidong Yang, Ziming Hu, Zhang Liu, Yangyang Ao, Ningjian 出版年：2017; We prepared a novel hemostatic material using chitosan (CS), alginate, and Bletilla striata, which showed good biocompatibility and hemostatic properties. Alginate-calcium porous microspheres (Alg) were prepared by emuls...

Marine Collagen Peptides from the Skin of Nile Tilapia (Oreochromis niloticus): Characterization and Wound Healing Evaluation: MARINE DRUGSHu, Zhang Yang, Ping Zhou, Chunxia Li, Sidong Hong, Pengzhi 出版年：2017; Burns can cause tremendous economic problems associated with irreparable harm to patients and their families. To characterize marine collagen peptides (MCPs) from the skin of Nile tilapia (Oreochromis niloticus), molecul...

Chitosan oligosaccharide-mediated attenuation of LPS-induced inflammation in IPEC-J2 cells is related to the TLR4/NF-kappa B signaling pathway: CARBOHYDRATE POLYMERSShi, Lin Fang, Biao Yong, Yanhong Li, Xuewen Gong, Dongliang Li, Junyu Yu, Tianyue Gooneratne, Ravi Gao, Zhenhua Li, Sidong Ju, Xianghong 出版年：2019; The protective mechanism of chitosan oligosaccharide (COS) against lipopolysaccharides (LPS) -induced inflammatory responses in IPEC-J2 and in mice with DSS dextran sulfate sodium (DSS) -induced colitis is reported. Upon...

Anti-Aging Effect of Chitosan Oligosaccharide on D-Galactose-Induced Subacute Aging in Mice: MARINE DRUGSKong, Song-Zhi Li, Ji-Cheng Li, Si-Dong Liao, Ming-Neng Li, Cheng-Peng Zheng, Pin-Jin Guo, Min-Hui Tan, Wei-Xiang Zheng, Zhao-Hui Hu, Zhang 出版年：2018; Chitosan oligosaccharide (COS), a natural polysaccharide with good antioxidant and anti-inflammatory properties, is the depolymerized product of chitosan possessing various biological activities. The present study was de...

Preparation of the chitosan/poly(glutamic acid)/alginate polyelectrolyte complexing hydrogel and study on its drug releasing property: CARBOHYDRATE POLYMERSChen, Yu Yan, Xiaoting Zhao, Jian Feng, Huaiyu Li, Puwang Tong, Zongrui Yang, Ziming Li, Sidong Yang, Jueying Jin, Shaohua 出版年：2018; In the current study, a novel semi-dissolution/acidification/sol-gel transition (SD-A-SGT) method was explored for the preparation of polyelectrolyte complexing (PEC) composite hydrogels with natural polymers only. A chi...

A sodium alginate-based sustained-release IPN hydrogel and its applications: RSC ADVANCESZou, Zuhao Zhang, Bijun Nie, Xiaoqin Cheng, Yu Hu, Zhang Liao, Mingneng Li, Sidong 出版年：2020; Interpenetrating polymer network (IPN) hydrogels are crosslinked by two or more polymer networks, providing free volume space in the three-dimensional network structure, and providing conditions for the sustained and con...

Cerium oxide immobilized reduced graphene oxide hybrids with excellent microwave absorbing performance: PHYSICAL CHEMISTRY CHEMICAL PHYSICSWang, Zhongqi Zhao, Pengfei He, Dongning Cheng, Yuan Liao, Lusheng Li, Sidong Luo, Yongyue Peng, Zheng Li, Puwang 出版年：2018; Microwave absorbing materials with high absorption over a broad bandwidth when they have a small thickness are strongly desired due to their widespread applications. Herein, cerium oxide immobilized reduced graphene oxid...

Antimicrobial sodium alginate dressing immobilized with polydopamine-silver composite nanospheres: COMPOSITES PART B-ENGINEERINGLiang, Limei Hou, Tingting Ouyang, Qianqian Xie, Lei Zhong, Saiyi Li, Puwang Li, Sidong Li, Chengpeng 出版年：2020; To endow antibacterial activity and maintain good porosity, oxidized sodium alginate (OSA) sponge was functionalized via polydopamine/silver composite nanospheres (PDA/AgNSs). It is found that uniform PDA spheres (around...

Chitosan hydrogel in combination with marine peptides from tilapia for burns healing: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESOuyang, Qian-Qian Hu, Zhang Lin, Zhen-Peng Quan, Wei-Yan Deng, Yi-Feng Li, Si-Dong Li, Pu-Wang Chen, Yu 出版年：2018; The purpose of this study was to develop a promising burns dressing. Chiosan (CS) has been widely used as biomaterials, in combination with marine peptides (MPs) extracted from seawater cultured Tilapia, the newly develo...

Catechol functionalized chitosan/active peptide microsphere hydrogel for skin wound healing: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESZhang, Dongying Ouyang, Qianqian Hu, Zhang Lu, Sitong Quan, Weiyan Li, Puwang Chen, Yu Li, Sidong 出版年：2021; Chitosan-based thermosensitive hydrogels have been widely used in drug delivery and tissue engineering, but their poor bioactivity has limited their further applications. Integral active oyster peptide microspheres (OPM)...

Mussel-Inspired Catechol-Functionalized Hydrogels and Their Medical Applications: MOLECULESQuan, Wei-Yan Hu, Zhang Liu, Hua-Zhong Ouyang, Qian-Qian Zhang, Dong-Ying Li, Si-Dong Li, Pu-Wang Yang, Zi-Ming 出版年：2019; Mussel adhesive proteins (MAPs) have a unique ability to firmly adhere to different surfaces in aqueous environments via the special amino acid, 3,4-dihydroxyphenylalanine (DOPA). The catechol groups in DOPA are a key gr...

Anti-photoaging effects of chitosan oligosaccharide in ultraviolet-irradiated hairless mouse skin: EXPERIMENTAL GERONTOLOGYKong, Song-Zhi Li, Dong-Dong Luo, Hui Li, Wen-Jie Huang, Yong-Mei Li, Ji-Cheng Hu, Zhang Huang, Na Guo, Min-Hui Chen, Yao Li, Si-Dong 出版年：2018; Skin photoaging (SP) is a premature skin-aging damage after repeated exposure to ultraviolet (UV) radiation, mainly characterized by oxidative stress and inflammatory disequilibrium, which makes skin show the typical sym...

Investigation of the Effects of Molecular Parameters on the Hemostatic Properties of Chitosan: MOLECULESHu, Zhang Lu, Sitong Cheng, Yu Kong, Songzhi Li, Sidong Li, Chengpeng Yang, Lei 出版年：2018; Hemorrhea is one of the major problems in war, trauma care, and surgical operation that threaten the life of the injured and patients. As a novel polymeric hemostatic agent, biodegradable chitosan can stop bleeding throu...

Sponges of Carboxymethyl Chitosan Grafted with Collagen Peptides for Wound Healing: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESCheng, Yu Hu, Zhang Zhao, Yuntao Zou, Zuhao Lu, Sitong Zhang, Bijun Li, Sidong 出版年：2019; Burns are physically debilitating and potentially fatal injuries. Two marine biomaterials, carboxymethyl chitosan (CMC) and collagen peptides (COP), have emerged as promising burn dressings. In this paper, sponges of car...

Hierarchical cerium oxide anchored multi-walled carbon nanotube hybrid with synergistic effect for microwave attenuation: COMPOSITES PART B-ENGINEERINGWang, Zhongqi Zhao, Pengfei Li, Puwang Li, Sidong Liao, Lusheng Luo, Yongyue Peng, Zheng He, Dongning Cheng, Yuan 出版年：2019; Microwave absorbing materials with light weight, high efficiency and broad effective bandwidth are strongly desired due to their widespread applications in military and civil fields. Here, hierarchical cerium oxide ancho...

Application of Chitosan, Chitooligosaccharide, and Their Derivatives in the Treatment of Alzheimer's Disease: MARINE DRUGSOuyang, Qian-Qian Zhao, Shannon Li, Si-Dong Song, Cai 出版年：2017; Classic hypotheses of Alzheimer's disease (ad) include cholinergic neuron death, acetylcholine (ACh) deficiency, metal ion dynamic equilibrium disorder, and deposition of amyloid and tau. Increased evidence suggests neur...

Construction of a composite sponge containing tilapia peptides and chitosan with improved hemostatic performance: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESOuyang, Qianqian Hou, Tingting Li, Chengpeng Hu, Zhang Liang, Limei Li, Sidong Zhong, Qingkun Li, Puwang 出版年：2019; Despite superior hemostasis and repair function, tilapia peptide's application as wounding dressing is greatly limited due to its poor biostability. To expand its application in wounding dressing area, chitosan (CS), wit...

Preparation of hydroxylated lecithin complexed iodine/carboxymethyl chitosan/sodium alginate composite membrane by microwave drying and its applications in infected burn wound treatment: CARBOHYDRATE POLYMERSChen, Yu Qiu, Haiying Dong, Miheng Cheng, Bin Jin, Yiguang Tong, Zongrui Li, Puwang Li, Sidong Yang, Ziming 出版年：2019; Improving the antibacterial properties of membrane wound dressings of natural polymers is crucial. Iodine is an important safe inorganic antibacterial agent, but was confined in the composition with polymer membranes due...

Self-assembled amphiphilic chitosan nanomicelles to enhance the solubility of quercetin for efficient delivery: COLLOIDS AND SURFACES B-BIOINTERFACESWang, Hui Yang, Ziming He, Zuyu Zhou, Chuang Wang, Chao Chen, Yu Liu, Xianwu Li, Sidong Li, Puwang 出版年：2019; Quercetin (QCT) has important functions such as antioxidant, anti-inflammatory and anticancer. However, its applications in food and in drug are restricted owing to its poor water solubility. In this work, a novel amphip...

海藻酸钙多孔微球-白芨多糖复合止血粉的制备及止血性能评价: 《高分子通报》王超罗文峰李普旺李思东杨子明胡章敖宁建出版年：2017; 海藻酸盐具有良好的生物相容性、可降解性、止血、抗菌、促愈合等特性,而中药白芨中的白芨多糖具有收敛止血、消肿生肌的功效。用海藻酸盐和白芨多糖为原料,采用冷冻干燥技术制备海藻酸钙多孔微球-白芨多糖复合止血粉,对其吸水速率进行...; 关键词：海藻酸盐微球白芨多糖止血 被引量：30

Chitosan-Gentamicin Conjugate Hydrogel Promoting Skin Scald Repair: MARINE DRUGSYan, Tingting Kong, Songzhi Ouyang, Qianqian Li, Chengpeng Hou, Tingting Chen, Yu Li, Sidong 出版年：2020; Our earlier research indicated that chitosan-gentamicin conjugate (CS-GT) possesses superior antimicrobial activity and good water solubility. To develop CS-GT-based scald dressings, the antibacterial properties of CS-GT...

基础化学实验教学模式创新探讨: 《实验技术与管理》蔡鹰李思东杨磊黄娜吴湛霞出版年：2018; 在认真考虑基础化学实验教学存在的问题和面临的时代背景要求的基础上,提出将基础化学实验教学传统模式和慕课、翻转课堂等教学方法中的优点进行融合,重新设计实验教学教案结构和要求,充分发挥手机APP和"种子学生"的作用,调整教师...; 关键词：基础化学实验教学模式创新 被引量：27

Preparation of chitosan-Cu2+/NH3 physical hydrogel and its properties: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESLi, Peng Feng, Zhipan Yu, Ziyang Chen, Yu Li, Puwang Yang, Ziming Li, Sidong Jin, Shaohua 出版年：2019; Chitosan (CTS) physical hydrogels crosslinked under gaseous ammonia atmospheres have attracted considerable attentions for their abilities to maximize the biological activities of CTS while maintaining their biocompatibi...

Synthesis of gentamicin-grafted-chitosan with improved solubility and antibacterial activity: REACTIVE & FUNCTIONAL POLYMERSYan, Tingting Li, Chengpeng Ouyang, Qianqian Zhang, Dongying Zhong, Qingkun Li, Puwang Li, Sidong Yang, Ziming Wang, Tao Zhao, Qingxia 出版年：2019; Due to superior properties, chitosan (CS) has been widely applied in health field. However its acid-solubility and poor antimicrobial activity compromise its safety and applications, respectively. To enhance its water-so...

Marine collagen peptide grafted carboxymethyl chitosan: Optimization preparation and coagulation evaluation: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESCheng, Yu Lu, Sitong Hu, Zhang Zhang, Bijun Li, Sidong Hong, Pengzhi 出版年：2020; Uncontrolled bleeding has always been a sudden accident, which is the main cause of casualties in war trauma, emergency events and surgical operations. Rapid hemostatic materials can effectively reduce casualties and sav...

Chitosan-Based Thermo-Sensitive Hydrogel Loading Oyster Peptides for Hemostasis Application: MATERIALSZhang, Dongying Hu, Zhang Zhang, Lingyu Lu, Sitong Liang, Fengyan Li, Sidong 出版年：2020; Uncontrolled massive hemorrhage is one of the principal causes of death in trauma emergencies. By using catechol-modified chitosan (CS-C) as the matrix material and beta glycerol phosphate (beta-GP) as a thermo-sensitive...

Preparation of nano-hydroxyapatite/chitosan/tilapia skin peptides hydrogels and its burn wound treatment: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESOuyang Qianqian Kong Songzhi Huang Yongmei Ju Xianghong Li Sidong Li Puwang Luo Hui 出版年：2021; There is an urgent need for wound dressings to treat partial-thickness burns. Hydrogels are a promising material that can maintain hydration to promote necrotic tissue removal. Tilapia peptides (TP) and hydroxyapatite (H...

Thermal degradation of agar: Mechanism and toxicity of products: FOOD CHEMISTRYOuyang, Qian-Qian Hu, Zhang Li, Si-Dong Quan, Wei-Yan Wen, Li-Li Yang, Zi-Ming Li, Pu-Wang 出版年：2018; The mechanism of the thermal degradation and the toxicity of the thermal degradation products of agar were studied using TG/DTA, Fourier-transform infrared spectroscopy and pyrolysis gas chromatography/mass spectrometry....

Elastic, super-hydrophobic and biodegradable chitosan sponges fabricated for oil/water separation: JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERINGLiang, Fengyan Hou, Tingting Li, Sidong Liao, Lusheng Li, Puwang Li, Chengpeng 出版年：2021; Due to easy availability and biodegradability, chitosan (CS)-based porous adsorbents have attracted significant interest in oil-spill and organic solvent removal. Herein, a multi-network CS-based sponge was fabricated vi...

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