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简纪常，二级教授，博士，博士生导师，现任研究生院院长。教育部高等学校水产类专业教学指导委员会委员，广东省水产经济动物病原生物学及流行病学重点实验室和水产经济动物病害广东省高等学校重点实验室副主任。曾被评为湛江市“十大”优秀青年、广东省教工委优秀共产党员和湛江市五一劳动奖章。入选广东省普通高等学校“千百十工程”省级培养对象、广东省扬帆计划高层次人才。中国水产学会理事、中国水产学会鱼病专业委员会委员，中国微生物学会海洋微生物学分会理事、国际鱼类免疫学会员、广东省海洋与湖沼学会和中国海洋学会热带海洋分会常务理事、湛江市水产动物疾病防治学会召集人。领导的... 详细>>

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共 549 条记录，以下是 1-30

Effects of traditional Chinese medicine on nonspecific immunity and disease resistance of large yellow croaker, Pseudosciaena crocea (Richardson): AQUACULTUREJian, JC Wu, ZH 出版年：2003; The influence of traditional Chinese medicine (TCM) formulated from Astragalus Root (Radix astragalin seu Hedysari) and Chinese Angelica Root (Radix angelicae sinensis) at the rate of 5:1 (w/w) on nonspecific immunity in...

Effects of a commercial probiotic BS containing Bacillus subtilis and Bacillus licheniformis on growth, immune response and disease resistance in Nile tilapia, Oreochromis niloticus: FISH & SHELLFISH IMMUNOLOGYAbarike, Emmanuel Delwin Cai, Jia Lu, Yishan Yu, Huang Chen, Lihua Jian, Jichang Tang, Jufen Jun, Liang Kuebutornye, Felix K. A. 出版年：2018; The present study evaluated a commercial probiotic designated as BS (a mix of B. subtilis and B. licheniformis) to ascertain its efficacy and the dose necessary to improve growth, immune response, and disease resistance ...

中草药对建鲤非特异性免疫功能的影响: 《大连水产学院学报》简纪常吴灶和出版年：2002; 用添加中草药的鲤配合饲料饲喂建鲤(Cyprinnus var．Jian)后,测定了建鲤非特异性免疫指标。饲喂药饵Ⅰ 10、15、30 d后,氯化硝基四氮唑兰(NBT)阳性细胞数分别为 27±3．45、39±6．04和 3...; 关键词：非特异性免疫功能建鲤中草药 NBT阳性细胞溶菌酶免疫增强剂饲料添加剂 被引量：135

Effect of marine red yeast Rhodosporidium paludigenum on growth and antioxidant competence of Litopenaeus vannamei: AQUACULTUREYang, Shi-Ping Wu, Zao-He Jian, Ji-Chang Zhang, Xing-Zhong 出版年：2010; The effects of orally administered marine red yeast Rhodosporidium paludigenum on growth performance and antioxidant competence of Litopenaeus vannamei were evaluated in a six-week feeding trial. The shrimps were fed wit...

Complete Genome Sequence of Streptococcus agalactiae ZQ0910, a Pathogen Causing Meningoencephalitis in the GIFT Strain of Nile Tilapia (Oreochromis niloticus): JOURNAL OF BACTERIOLOGYWang, Bei Jian, Jichang Lu, Yishan Cai, Shuanghu Huang, Yuchong Tang, Jufen Wu, Zaohe 出版年：2012; Streptococcus agalactiae (group B streptococcus [GBS]) is a pathogen that causes meningoencephalitis in Nile tilapia (Oreochromis niloticus). Here, we reported the complete genome sequence of S. agalactiae strain ZQ0910,...

CHARACTERIZATION OF PATHOGENIC AEROMONAS VERONII BV. VERONII ASSOCIATED WITH ULCERATIVE SYNDROME FROM CHINESE LONGSNOUT CATFISH (LEIOCASSIS LONGIROSTRIS GUNTHER): BRAZILIAN JOURNAL OF MICROBIOLOGYCai, Shuang-Hu Wu, Zao-He Jian, Ji-Chang Lu, Yi-Shan Tang, Ju-Feng 出版年：2012; 273 bacterial strains were isolated from 20 Chinese longsnout catfish samples. The biochemical characteristics of all strains conformed to the species description of Aeromonas veronii bv. veronii on the basis of Vitek GN...

Comprehensive identification and profiling of Nile tilapia (Oreochromis niloticus) microRNAs response to Streptococcus agalactiae infection through high-throughput sequencing: FISH & SHELLFISH IMMUNOLOGYWang, Bei Gan, Zhen Cai, Shuanghu Wang, Zhongliang Yu, Dapeng Lin, Ziwei Lu, Yishan Wu, Zaohe Jian, Jichang 出版年：2016; MicroRNAs are a kind of small non-coding RNAs that participate in various biological processes. Deregulated microRNA expression is associated with several types of diseases. Tilapia (Oreochromis niloticus) is an importan...

Cloning and expression of heat shock protein 70 gene in the haemocytes of pearl oyster (Pinctada fucata, Gould 1850) responding to bacterial challenge: FISH & SHELLFISH IMMUNOLOGYWang, Zhongliang Wu, Zaohe Jian, Jichang Lu, Yishan 出版年：2009; The cDNA of pearl oyster Pinctada fucata Hsp70 (designated PFHsp70) was cloned by EST and rapid amplification of cDNA ends (RACE) techniques. The full length of PFHsp70 cDNA was 2376 bp, consisting of a 5'-terminal untra...

Immunostimulatory effects of artificial feed supplemented with a Chinese herbal mixture on Oreochromis niloticus against Aeromonas hydrophila: FISH & SHELLFISH IMMUNOLOGYTang, Jufen Cai, Jia Liu, Ran Wang, Jiamin Lu, Yishan Wu, Zaohe Jian, Jichang 出版年：2014; The effects of a Chinese herbal mixture (CHM) composed of astragalus, angelica, hawthorn, Licorice root and honeysuckle on immune responses and disease resistant of Nile tilapia (Oreochromis niloticus GIFT strain) were i...

Influence of traditional Chinese medicine and Bacillus species (TCMBS) on growth, immune response and disease resistance in Nile tilapia, Oreochromis niloticus: AQUACULTURE RESEARCHAbarike, Emmanuel Delwin Jian, Jichang Tang, Jufen Cai, Jia Yu, Huang Chen Lihua Jun, Liang 出版年：2018; Multispecies herbs and probiotic bacteria offered to fish might enhance their immune response and increase disease resistance, but the dose effects of herbal-probiotic application remain unclear. Therefore, the effect of...

Single-cell RNA-seq reveals different subsets of non-specific cytotoxic cells in teleost: GENOMICSNiu, Jinzhong Huang, Yu Liu, Xinchao Zhang, Zhiqiang Tang, Jufen Wang, Bei Lu, Yishan Cai, Jia Jian, Jichang 出版年：2020; Non-specific cytotoxic cells (NCC) are important cytotoxic leukocytes in teleost immune system. However, the NCC subsets have not been clarified. Thus, we create a comprehensive cell map of similar to 24,062 head kidney-...

NK-lysin from Oreochromis niloticus improves antimicrobial defence against bacterial pathogens: FISH & SHELLFISH IMMUNOLOGYHuang, Yu Zheng, Qi Niu, Jinzhong Tang, Jufen Wang, Bei Abarike, Emmanuel Delwin Lu, Yishan Cai, Jia Jian, Jichang 出版年：2018; NK-lysin, an effector of cytotoxic T cells and natural killer cells, is a potent antimicrobial peptide widely distributed in mammals. Homologues of NK-lysin have been discovered in several teleost species, but only sever...

Strategies to enhance tilapia immunity to improve their health in aquaculture: REVIEWS IN AQUACULTUREWang, Bei Thompson, Kim D. Wangkahart, Eakapol Yamkasem, Jidapa Bondad-Reantaso, Melba G. Tattiyapong, Puntanat Jian, Jianchang Surachetpong, Win 出版年：2023; Various emerging and re-emerging diseases, such as streptococcosis, tilapia lake virus disease and infectious spleen and kidney necrosis virus disease, have had a significant economic impact on the tilapia industry over ...

恩诺沙星在眼斑拟石首鱼体内的药物代谢动力学: 《中国兽医学报》简纪常吴灶和陈刚出版年：2005; 应用反相高效液相色谱法 (RP- HPL C)研究了恩诺沙星在眼斑拟石首鱼 (Sciaenops ocellatus)体内的药物代谢动力学。实验数据经 DAS药代动力学分析软件分析后得出 :腹腔注射组血浆的药时数据符合一...; 关键词：眼斑拟石首鱼恩诺沙星药物代谢动力学反相高效液相色谱法 被引量：45

Molecular characterization and expression of CD2BP2 in Nile tilapia (Oreochromis niloticus) in response to Streptococcus agalactiae stimulus: GENEGan, Zhen Wang, Bei Lu, Yishan Cai, Shuanghu Cai, Jia Jian, JiChang Wu, Zaohe 出版年：2014; CD2BP2 (CD2 cytoplasmic tail binding protein 2), one of several proteins interacting with the cytoplasmic tail of CD2, plays a crucial role in CD2-triggered T cell activation and nuclear splicing. The studies on CD2BP2 h...

Construction of a Vibrio alginolyticus hopPmaJ (hop) mutant and evaluation of its potential as a live attenuated vaccine in orange-spotted grouper (Epinephelus coioides): FISH & SHELLFISH IMMUNOLOGYPang, Huanying Qiu, Mingsheng Zhao, Jingmin Hoare, Rowena Monaghan, Sean J. Song, Dawei Chang, Yunsheng Jian, Jichang 出版年：2018; Vibrio alginolyticus, a bacterial pathogen in fish and humans, expresses a type III secretion system (T3SS) that is critical for pathogen virulence and disease development. However, little is known about the associated e...

Transcriptome analysis of the pearl oyster (Pinctada fucata) hemocytes in response to Vibrio alginolyticus infection: GENEWang, Zhongliang Wang, Bei Chen, Gang Jian, Jichang Lu, Yishan Xu, Youhou Wu, Zaohe 出版年：2016; The pearl oyster Pinctada fucata is cultured widely for production of marine pearls in China, while mass mortalities, likely related to pathogenic infections, have occurred frequently in juvenile, mother and operated oys...

利用有益微生物改善养殖生态环境的研究: 《湛江海洋大学学报》陈家长简纪常胡庚东吴伟瞿建宏出版年：2002; 研究了噬菌蛭弧菌在实验室条件下对水产养殖中常见病菌的裂解能力及噬菌蛭弧菌和光合细菌对池塘生态环境的改善作用。结果表明 ,噬菌蛭菌对嗜水气单胞菌具有裂解作用 ,噬菌蛭弧菌和光合细菌结合使用对养殖环境具有明显的改善作用。 2...; 关键词：有益微生物养殖生态环境噬菌蛭弧菌光合细菌嗜水气单胞菌 被引量：38

Conservation of structural and interactional features of CD28 and CD80/86 molecules from Nile tilapia (Oreochromis niloticus): FISH & SHELLFISH IMMUNOLOGYHuang, Yu Wang, Zhiwen Zheng, Qi Tang, Jufen Cai, Jia Lu, Yishan Jian, Jichang 出版年：2018; Interaction of CD28 with CD80 or CD86 molecules provides a costimulatory signals required in T cell activation. In this study, we cloned and analyzed a CD28 gene (On-CD28) and a CD80/86 gene (On-CD80/86) from Nile tilapi...

Short term starvation and re-feeding in Nile tilapia (Oreochromis niloticus, Linnaeus 1758): Growth measurements, and immune responses: AQUACULTURE REPORTSSakyi, Michael Essien Cai, Jia Tang, Jufen Xia, Liqun Li, Pengfei Abarike, Emmanuel Delwin Kuebutornye, Felix Kofi Agbeko Jian, Jichang 出版年：2020; The effects of short term starvation and re-feeding to satiation on compensatory growth performance, haematological parameters, biochemical parameters, and immune responses were investigated in Oreochromis niloticus of a...

Molecular characterization and expression of interleukin-10 and interleukin-22 in golden pompano (Trachinotus ovatus) in response to Streptococcus agalactiae stimulus: FISH & SHELLFISH IMMUNOLOGYPeng, Yinhui Cai, Xiaohui Zhang, Guoyin Wang, Junlin Li, Yuan Wang, Zhiwen Wang, Bei Xiong, Xiangying Wu, Zaohe Jian, Jichang 出版年：2017; In the present study, members of the interleukin (IL)-10 family of cytokines, including IL-10 (TOIL-10) and IL-22 (TOIL-22) of golden pompano (Trachinotus ovatus), were cloned for the first time, and their expression pat...

VscO, a putative T3SS chaperone escort of Vibrio alginolyticus, contributes to virulence in fish and is a target for vaccine development: FISH & SHELLFISH IMMUNOLOGYZhou, Zejun Pang, Huanying Ding, Yu Cai, Jia Huang, Yucong Jian, Jichang Wu, Zaohe 出版年：2013; Type III secretion system (T3SS) in Vibrio alginolyticus is essential for its pathogenesis. VscO's homologous proteins FliJ, InvI and YscO have been suggested to be putative chaperone escorts although its function in V. ...

Loop-mediated isothermal amplification method for rapid detection of Vibrio alginolyticus, the causative agent of vibriosis in mariculture fish: LETTERS IN APPLIED MICROBIOLOGYCai, S. H. Lu, Y. S. Wu, Z. -H. Jian, J. C. Wang, B. Huang, Y. C. 出版年：2010; Aims: The purpose of this study was to develop a loop-mediated isothermal amplification (LAMP) method for the rapid, sensitive and simple detection of Vibrio alginolyticus in mariculture fish. Methods and Results: LAMP p...

Fish Galectin8-Like Exerts Positive Regulation on Immune Response Against Bacterial Infection: FRONTIERS IN IMMUNOLOGYNiu, Jinzhong Huang, Yu Liu, Xinchao Wu, Fenglei Tang, Jufen Wang, Bei Lu, Yishan Cai, Jia Jian, Jichang 出版年：2020; Galectin-8 is a member of the galectin family that is involved in immune response against pathogens. However, the roles of fish galectin-8 during pathogen infection require comprehensive studies. In this study, a galecti...

A tandem-repeat galectin involved in innate immune response of the pearl oyster Pinctada fucata: MARINE GENOMICSWang, Zhongliang Jian, Jichang Lu, Yishan Wang, Bei Wu, Zaohe 出版年：2011; The cDNA of a tandem-repeat galectin from the pearl oyster Pinctada fucata (designated PfGal) was cloned by expressed sequence tag (EST) and rapid amplification of cDNA ends (RACE) techniques. The full-length cDNA of PfG...

A mixture of Chinese herbs and a commercial probiotic Bacillus species improves hemato-immunological, stress, and antioxidant parameters, and expression of HSP70 and HIF-1α mRNA to hypoxia, cold, and heat stress in Nile tilapia, Oreochromis niloticus: AQUACULTURE REPORTSAbarike, Emmanuel Delwin Jian, Jichang Tang, Jufen Cai, Jia Sakyi, Essien M. Kuebutornye, Felix K. A. 出版年：2020; A 56-day feeding trial was performed to evaluate the effect of herbal-probiotic supplements comprising a mixture of Chinese herbs (CH) (i.e., Astragalus membranaceus, Angelica sinensis, and Crataegus hupehensis) and or c...

海水网箱养殖军曹鱼弧菌病病原的分离及其特性: 《中国兽医学报》简纪常吴灶和陈刚曾敏玲出版年：2003; 从海水网箱养殖的患病军曹鱼 (Rachycentron canadum)的肾脏、肝脏等实质器官及腹水中分离出 1株致病菌即JA- 4 6菌。其特点如下 :革兰氏阴性短杆菌 ,极端单鞭毛 ,大小为 (1～ 2 )μm× (...; 关键词：军曹鱼海水网箱养殖弧菌病创伤弧菌药敏试验生物学特性 被引量：33

卵形鲳鲹结节病病原的分离与鉴定: 《广东海洋大学学报》黄郁葱简纪常吴灶和鲁义善余坦健出版年：2008; 从湛江港、阳江闸坡海水网箱养殖的患结节病卵形鲳鲹(Trachinotus ovatus)中分离一株细菌,回归感染结果证明该菌是引起卵形鲳鲹结节病的病原,对卵形鲳鲹半致死浓度为45 g-1。该菌株呈革兰阳性,好氧,具有弱抗...; 关键词：卵形鲳鲹结节病诺卡氏菌 16S rDNA 被引量：33

A comprehensive profile of the tilapia (Oreochromis niloticus) circular RNA and circRNA-miRNA network in the pathogenesis of meningoencephalitis of teleosts: MOLECULAR OMICSFan, Bolin Chen, Funuan Li, Yuan Wang, Zhongliang Wang, Zhiwen Lu, Yishan Wu, Zaohe Jian, Jichang Wang, Bei 出版年：2019; The pathogenesis of tilapia meningoencephalitis is still unclear, where the involvement of circRNA is considered for its active role as a `` miRNA sponge''. Therefore, we aimed to investigate the profile of circRNA in ti...

Traditional Chinese Medicine Enhances Growth, Immune Response, and Resistance to Streptococcus agalactiae in Nile Tilapia: JOURNAL OF AQUATIC ANIMAL HEALTHAbarike, Emmanuel Delwin Jian, Jichang Tang, Jufen Cai, Jia Yu, Huang Chen, Lihua 出版年：2019; Herbal supplements are suitable for improving fish health and combating diseases in fish culture. However, the mechanism of action of many herbal mixtures remains unclear. This study was conducted to evaluate the effects...

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