检索结果分析
成果/Result
成果类型
- 期刊论文
- 学位论文
- 专利
- 会议论文
- 科技成果
- 标准
- 专著
- 产品
- 科技报告
- 政策法规
- 内部文献
- 报纸
- Mussel-Inspired Catechol-Functionalized Hydrogels and Their Medical Applications
- MOLECULESQuan, Wei-Yan Hu, Zhang Liu, Hua-Zhong Ouyang, Qian-Qian Zhang, Dong-Ying Li, Si-Dong Li, Pu-Wang Yang, Zi-Ming 出版年：2019
- Mussel adhesive proteins (MAPs) have a unique ability to firmly adhere to different surfaces in aqueous environments via the special amino acid, 3,4-dihydroxyphenylalanine (DOPA). The catechol groups in DOPA are a key gr...
- Effect of carboxymethylation on properties of fucoidan from <i>Laminaria japonica</i>: Antioxidant activity and preservative effect on strawberry during cold storage
- POSTHARVEST BIOLOGY AND TECHNOLOGYDuan, Zhenhua Duan, Weiwen Li, Fangping Li, Yanqun Luo, Ping Liu, Huazhong 出版年：2019
- Carboxymethylation modification is commonly used for improving physicochemical and biological properties of nature polysaccharides, effect of carboxymethylation on property of fucoidan from Laminaria japonica (FL) is sti...
- Molecular Targets and Related Biologic Activities of Fucoidan: A Review
- MARINE DRUGSLin, Zhen Tan, Xiaohui Zhang, Yu Li, Fangping Luo, Ping Liu, Huazhong 出版年：2020
- Fucoidan-a marine natural active polysaccharide derived from brown algae with a variety of medicinal activities and low toxicity-has been used as clinical drug for renal diseases for nearly 20 years. The pharmacological ...
- Production Inhibition and Excretion Promotion of Urate by Fucoidan from <i>Laminaria japonica</i> in Adenine-Induced Hyperuricemic Mice
- MARINE DRUGSZhang, Dayan Liu, Huazhong Luo, Ping Li, Yanqun 出版年：2018
- This work aims to explore the amelioration of fucoidan on adenine-induced hyperuricemia and hepatorental damage. Adenine-induced hyperuricemic mice were administered with fucoidan, allopurinol and vehicle control respect...
- Inhibition of acrolein-induced autophagy and apoptosis by a glycosaminoglycan from <i>Sepia esculenta</i> ink in mouse Leydig cells
- CARBOHYDRATE POLYMERSGu, Yi-Peng Yang, Xiao-Mei Luo, Ping Li, Yan-Qun Tao, Ye-Xing Duan, Zhen-Hua Xiao, Wei Zhang, Da-Yan Liu, Hua-Zhong 出版年：2017
- In our recent reports, a squid ink polysaccharide (SIP) was found having preventive activity against cyclophosphamide induced damage in mouse testis and ovary. Here we further reveal the regulative mechanism of SIP again...
- Effect of Carboxymethylation and Phosphorylation on the Properties of Polysaccharides from <i>Sepia esculenta</i> Ink: Antioxidation and Anticoagulation In Vitro
- MARINE DRUGSLiu, Huazhong Li, Fangping Luo, Ping 出版年：2019
- To investigate the effect of carboxymethylation and phosphorylation modification on Sepia esculenta ink polysaccharide (SIP) properties, this study prepared carboxymethyl SIP (CSIP) with the chloracetic acid method, and ...
- Inhibition of chemotherapy-induced apoptosis of testicular cells by squid ink polysaccharide
- EXPERIMENTAL AND THERAPEUTIC MEDICINEGu, Yi-Peng Yang, Xiao-Mei Duan, Zhen-Hua Luo, Ping Shang, Jiang-Hua Xiao, Wei Tao, Ye-Xing Zhang, Da-Yan Zhang, Yun-Bo Liu, Hua-Zhong 出版年：2017
- The aim of this study was to determine the mechanisms driving the protective effects of squid ink polysaccharide (SIP) against cyclophosphamide (CP)-induced testicular damage, focusing on germ cells. In the testes of mic...
- Fucoidan from <i>Laminaria japonica</i> Inhibits Expression of GLUT9 and URAT1 via PI3K/Akt, JNK and NF-κB Pathways in Uric Acid-Exposed HK-2 Cells
- MARINE DRUGSZhang, Yu Tan, Xiaohui Lin, Zhen Li, Fangping Yang, Chunyan Zheng, Haiying Li, Lingyu Liu, Huazhong Shang, Jianghua 出版年：2021
- This work aimed to investigate the effect of fucoidan (FPS) on urate transporters induced by uric acid (UA). The results showed that UA stimulated the expression of glucose transporter 9 (GLUT9) and urate transporter 1 (...
- A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides
- MARINE DRUGSLi, Fangping Luo, Ping Liu, Huazhong 出版年：2018
- Sepia ink polysaccharide (SIP) isolated from squid and cuttlefish ink is a kind of acid mucopolysaccharide that has been identified in three types of primary structures from squid (Illex argentinus and Ommastrephes bartr...
- Production, isolation and bioactive estimation of extracellular polysaccharides of green microalga <i>Neochloris oleoabundans</i>
- ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTSLi, Yanqun Wang, Caijuan Liu, Huazhong Su, Junbiao Lan, Christopher Q. Zhong, Min Hu, Xueqiong 出版年：2020
- Previous research revealed that green microalga Neochloris oleoabundans was able to excrete extracellular polysaccharides (EPS) in the media containing certain sugar, but detail researches on the production conditions an...
- Effect of fucoidan-based edible coating on antioxidant degradation kinetics in strawberry fruit during cold storage
- JOURNAL OF FOOD PROCESSING AND PRESERVATIONLuo, Ping Li, Fangping Liu, Huazhong Yang, Xiaomei Duan, Zhenhua 出版年：2020
- To further investigate fresh-keeping effect of fucoidan from Laminaria japonica (FL) on postharvest strawberry, this study assessed the degradation kinetics of antioxidant capacity and antioxidants in cold-stored strawbe...
- Beneficial effect of <i>Sepia esculenta</i> ink polysaccharide on cyclophosphamide-induced immunosuppression and ovarian failure in mice
- INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESLiu, Huazhong Zhang, Yunbo Li, Mingwei Luo, Ping 出版年：2019
- In order to investigate prevention of squid ink polysaccharide (SIP) against cyclophosphamide (CP) induced ovarian failure and immunosuppression in mice, female Kunming mice were subjected to intraperitoneal injection of...
- Squid Ink Polysaccharides Protect Human Fibroblast Against Oxidative Stress by Regulating NADPH Oxidase and Connexin43
- FRONTIERS IN PHARMACOLOGYChen, Ying Liu, Huazhong Huang, Hao Ma, Yuetang Wang, Ruihua Hu, Yong Zheng, Xiufen Chen, Chunmei Tang, Hongfeng 出版年：2020
- Oxidation injury to skin is one of the main reasons for skin aging. The aim of the present study was to explore the protective effect of squid ink polysaccharides and its mechanism of action against H2O2-induced dermal f...
- Squid ink polysaccharide prevents autophagy and oxidative stress affected by cyclophosphamide in Leydig cells of mice: a pilot study
- IRANIAN JOURNAL OF BASIC MEDICAL SCIENCESGu, Yi-Peng Yang, Xiao-Mei Duan, Zhen-Hua Shang, Jiang-Hua Luo, Ping Xiao, Wei Zhang, Da-Yan Liu, Hua-Zhong 出版年：2017
- Objective(s): The aim of this study was to explore the effects of Squid ink polysaccharide (SIP) on prevention of autophagy and oxidative stress induced by cyclophosphamide (CP) in Leydig cells of mice. Materials and Met...
- Grafting of 18β-Glycyrrhetinic Acid and Sialic Acid onto Chitosan to Produce a New Amphipathic Chitosan Derivative: Synthesis, Characterization, and Cytotoxicity
- MOLECULESQuan, Wei-Yan Kong, Song-Zhi Li, Si-Dong Liu, Hua-Zhong Ouyang, Qian-Qian Huang, Yong-Mei Luo, Hui 出版年：2021
- Chitosan is the only cationic polysaccharide found in nature. It has broad application prospects in biomaterials, but its application is limited due to its poor solubility in water. A novel chitosan derivative was synthe...
- Preventive Effects of Three Polysaccharides on the Oxidative Stress Induced by Acrylamide in a <i>Saccharomyces cerevisiae</i> Model
- MARINE DRUGSLin, Zhen Zhang, Yu Li, Fangping Tan, Xiaohui Luo, Ping Liu, Huazhong 出版年：2020
- Saccharomyces cerevisiaewas used as a model to explore the preventive effect of two marine polysaccharides separately derived fromSepia esculentaink (SIP) andLaminaria japonica(FL) as well as one terrestrial polysacchari...
- Polysaccharide from <i>Sepia esculenta</i> ink and cisplatin inhibit synergistically proliferation and metastasis of triple-negative breast cancer MDA-MB-231 cells
- IRANIAN JOURNAL OF BASIC MEDICAL SCIENCESLiu, Hua-Zhong Xiao, Wei Gu, Yi-Peng Tao, Ye-Xing Zhang, Da-Yan Du, Hui Shang, Jiang-Hua 出版年：2016
- Objective(s): This paper aims to investigate synergistic inhibition of polysaccharide from Sepia esculenta ink (SIP), a newly isolated marine polysaccharide in our laboratory, on breast cancer MDA-MB- 231 cells exposed t...
- Antioxidant, anticoagulant and thrombolytic properties of SIP-IV, a sulfated polysaccharide from<i> Sepia</i><i> esculenta</i> ink, and its derivatives
- FOOD BIOSCIENCELi, Fangping Lin, Zhen Wu, Yulian Luo, Ping Wu, Jiayi Liu, Huazhong 出版年：2022
- Carboxymethylated, phosphorylated and sulfated derivatives of SIP-IV, a polysaccharide derived from Sepia esculenta ink, were prepared and their antioxidant, anticoagulant and thrombolytic properties were evaluated. Data...
- Multi-omics based strategy for toxicity analysis of acrylamide in <i>Saccharomyces cerevisiae</i> model
- CHEMICO-BIOLOGICAL INTERACTIONSLin, Zhen Luo, Ping Huang, Dongmin Wu, Yulian Li, Fangping Liu, Huazhong 出版年：2021
- Although the toxicity of acrylamide (ACR) has been extensively investigated in different experimental models, its perturbations to multiple nodes of the cellular signaling network have not been systematically associated....
- Toxicologic effect of short-term enrofloxacin exposure on brain of Carassius auratus var. Pengze
- SCIENCE OF THE TOTAL ENVIRONMENTLin, Zhen Wan, Gen Wu, Jiayi Liu, Huazhong Zhang, Fan Tang, Xiaochen Ruan, Jiming 出版年：2023
- To further explore short-term exposure of enrofloxacin (ENR) induced toxicity in crucian carp brain that has been reported by our previous work, as well as the possible toxicological mechanisms, this study investigated t...
- An enzyme free fluorescence resonance transfer strategy based on hybrid chain reaction and triplex DNA for Vibrio parahaemolyticus
- SCIENTIFIC REPORTSTan, Xiao-Hui Li, Yu-Bin Liao, Yan Liu, Hua-Zhong 出版年：2020
- In this work, an enzyme-free fluorescence resonance energy transfer (FRET) strategy was established for rapid and specific detection of the DNA sequence from Vibrio parahaemolyticus (VP) using hybridization chain reactio...
- Effects of a sulfated glycosaminoglycan from<i> Sepia</i><i> esculenta</i> ink on transcriptional and metabolic profiles of<i> Saccharomyces</i><i> cerevisiae</i>
- CARBOHYDRATE POLYMERSLin, Zhen Luo, Ping Lin, Xuan Chen, Yini Zhang, Yu Li, Fangping Tan, Xiaohui Liu, Huazhong 出版年：2022
- Four fractions of water-extracted Sepia esculenta ink polysaccharides (SIP) were separated by dicthylaminoethy (DEAE) cellulose chromatography. The eluted fraction with the highest yield was characterized as a sulfate-ri...
- Structural characterization of a water-soluble acidic polysaccharide CSP-IV with potential anticoagulant activity from fruit pulp of<i> Clausena</i><i> lansium</i> (Lour.) Skeels Guifei
- INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESWu, Jiayi Zheng, Wenyan Luo, Ping Lin, Zhen Li, Fangping Liang, Linlin Liu, Huazhong 出版年：2024
- Four main water-soluble wampee fruit pulp polysaccharides, named CSP-I, CSP-II, CSP-III and CSP-IV, were isolated from Clausena lansium (Lour.) Skeels Guifei, therein CSP-IV content was higher than the others. All compon...
- Analysis of astaxanthin molecular targets based on network pharmacological strategies
- JOURNAL OF FOOD BIOCHEMISTRYLin, Zhen Li, Fangping Zhang, Yu Tan, Xiaohui Luo, Ping Liu, Huazhong 出版年：2021
- In order to further explore the potential pharmacological activity of astaxanthin (AST), network pharmacological approaches were employed in this work to systematically investigate its affinity targets, perturbed signali...
- Label-free colorimetric detection of divalent mercuric ions (Hg<SUP>2+</SUP>) based on T-Hg<SUP>2+</SUP>-T structure and exonuclease III dual-recycling and G-quadruplex-hemin DNAzyme amplification
- INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRYYuan, Jiaming Wu, Yulian Kang, Xinhuang Liu, Huazhong Li, Yubin 出版年：2020
- Detection of divalent mercury attracts great significance in most biological and environmental systems. In this study, a Thymine-divalent mercuric ions-Thymine (T-Hg2+-T) structure based colorimetric assay with Exonuclea...
- Modulation of the gut microbiota alleviates insulin resistance in type 2 diabetic mice by daucosterol from Eleocharis dulcis peel
- JOURNAL OF FUNCTIONAL FOODSYang, Xiaomei Gu, Yipeng Liu, Huazhong Shang, Feifei Koyama, Tomoyuki 出版年：2024
- Daucosterol, a natural saponin from Eleocharis dulcis peel, exhibited anti-hyperglycemic properties. This study investigated daucosterol's effects on glycemic control, insulin resistance, and gut microbiota in type 2 dia...
- Squid ink polysaccharide prevents chemotherapy induced injury in the testes of reproducing mice
- PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCESLuo, Ping Liu, Hua-Zhong Le, Xiao-Yan Du, Hui Kang, Xin-Huang 出版年：2018
- The present study was conducted to investigate the preventive effects of squid ink polysaccharides (SIP) on the damage of sperm and reproduction induced by cyclophosphamide that is most commonly used for treating clinica...
- The effect of melanin-free extract from <i>Sepia esculenta</i> ink on lipid peroxidation, protein oxidation and water-holding capacity of tilapia fillet during cold storage
- CHEMISTRY CENTRAL JOURNALDuan, Zhen-Hua Liu, Hua-Zhong Luo, Ping Gu, Yi-Peng Li, Yan-Qun 出版年：2018
- Background: Preservative effect of melanin-free extract of Sepia esculenta ink (MFESI) on Sparus latus fillet has been verified in our previous work. This study aims to further approach the mechanism of MFESI for extendi...
- Curcumin mediates autophagy and apoptosis in granulosa cells: a study of integrated network pharmacology and molecular docking to elucidate toxicological mechanisms
- DRUG AND CHEMICAL TOXICOLOGYLin, Zhen Liu, Huazhong Yang, Chunyan Zheng, Haiying Zhang, Yu Su, Weiming Shang, Jianghua 出版年：2022
- Curcumin (Cur) is a flavonoid derived from Curcuma longa L. that has been shown to have a variety of biological activities, but some previous studies have described its non-negligible negative effects on female reproduct...
- Fucoidan from<i> Laminaria</i><i> japonica</i> protects renal tubular epithelial cells from uric acid induced NLRP3-mediated pyroptosis through inhibition of NF-κB pathway
- JOURNAL OF ETHNOPHARMACOLOGYTan, Xiaohui Zhang, Yu Luo, Ping Lin, Zhen Li, Fangping Liu, Huazhong 出版年：2024
- Ethnopharmacological relevance: Hyperuricemia is a common metabolic disease with prominent morbidity, it can lead to many adverse effects and complications, such as chronic nephrosis. Fucoidan has been used as natural dr...
