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被引量:985H指数:18SCI-EXPANDED: 28EI: 14北大核心: 12CSCD: 10

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65 条 记 录,以下是 1-30

Chitosan-Based Composite Materials for Prospective Hemostatic Applications
MARINE DRUGSHu, Zhang Zhang, Dong-Ying Lu, Si-Tong Li, Pu-Wang Li, Si-Dong  出版年:2018
Effective hemostasis is vital to reduce the pain and mortality of patients, and the research and development of hemostatic materials are prerequisite for effective hemostasis. Chitosan (CS), with good biodegradability, b...
Preparation and evaluation of chitosan/alginate porous microspheres/Bletilla striata polysaccharide composite hemostatic sponges
CARBOHYDRATE POLYMERSWang, Chao Luo, Wenfeng Li, Puwang Li, Sidong Yang, Ziming Hu, Zhang Liu, Yangyang Ao, Ningjian  出版年:2017
We prepared a novel hemostatic material using chitosan (CS), alginate, and Bletilla striata, which showed good biocompatibility and hemostatic properties. Alginate-calcium porous microspheres (Alg) were prepared by emuls...
Marine Collagen Peptides from the Skin of Nile Tilapia (Oreochromis niloticus): Characterization and Wound Healing Evaluation
MARINE DRUGSHu, Zhang Yang, Ping Zhou, Chunxia Li, Sidong Hong, Pengzhi  出版年:2017
Burns can cause tremendous economic problems associated with irreparable harm to patients and their families. To characterize marine collagen peptides (MCPs) from the skin of Nile tilapia (Oreochromis niloticus), molecul...
Anti-Aging Effect of Chitosan Oligosaccharide on D-Galactose-Induced Subacute Aging in Mice
MARINE DRUGSKong, Song-Zhi Li, Ji-Cheng Li, Si-Dong Liao, Ming-Neng Li, Cheng-Peng Zheng, Pin-Jin Guo, Min-Hui Tan, Wei-Xiang Zheng, Zhao-Hui Hu, Zhang  出版年:2018
Chitosan oligosaccharide (COS), a natural polysaccharide with good antioxidant and anti-inflammatory properties, is the depolymerized product of chitosan possessing various biological activities. The present study was de...
A sodium alginate-based sustained-release IPN hydrogel and its applications
RSC ADVANCESZou, Zuhao Zhang, Bijun Nie, Xiaoqin Cheng, Yu Hu, Zhang Liao, Mingneng Li, Sidong  出版年:2020
Interpenetrating polymer network (IPN) hydrogels are crosslinked by two or more polymer networks, providing free volume space in the three-dimensional network structure, and providing conditions for the sustained and con...
Chitosan hydrogel in combination with marine peptides from tilapia for burns healing
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESOuyang, Qian-Qian Hu, Zhang Lin, Zhen-Peng Quan, Wei-Yan Deng, Yi-Feng Li, Si-Dong Li, Pu-Wang Chen, Yu  出版年:2018
The purpose of this study was to develop a promising burns dressing. Chiosan (CS) has been widely used as biomaterials, in combination with marine peptides (MPs) extracted from seawater cultured Tilapia, the newly develo...
Catechol functionalized chitosan/active peptide microsphere hydrogel for skin wound healing
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESZhang, Dongying Ouyang, Qianqian Hu, Zhang Lu, Sitong Quan, Weiyan Li, Puwang Chen, Yu Li, Sidong  出版年:2021
Chitosan-based thermosensitive hydrogels have been widely used in drug delivery and tissue engineering, but their poor bioactivity has limited their further applications. Integral active oyster peptide microspheres (OPM)...
Mussel-Inspired Catechol-Functionalized Hydrogels and Their Medical Applications
MOLECULESQuan, Wei-Yan Hu, Zhang Liu, Hua-Zhong Ouyang, Qian-Qian Zhang, Dong-Ying Li, Si-Dong Li, Pu-Wang Yang, Zi-Ming  出版年:2019
Mussel adhesive proteins (MAPs) have a unique ability to firmly adhere to different surfaces in aqueous environments via the special amino acid, 3,4-dihydroxyphenylalanine (DOPA). The catechol groups in DOPA are a key gr...
Anti-photoaging effects of chitosan oligosaccharide in ultraviolet-irradiated hairless mouse skin
EXPERIMENTAL GERONTOLOGYKong, Song-Zhi Li, Dong-Dong Luo, Hui Li, Wen-Jie Huang, Yong-Mei Li, Ji-Cheng Hu, Zhang Huang, Na Guo, Min-Hui Chen, Yao Li, Si-Dong  出版年:2018
Skin photoaging (SP) is a premature skin-aging damage after repeated exposure to ultraviolet (UV) radiation, mainly characterized by oxidative stress and inflammatory disequilibrium, which makes skin show the typical sym...
Investigation of the Effects of Molecular Parameters on the Hemostatic Properties of Chitosan
MOLECULESHu, Zhang Lu, Sitong Cheng, Yu Kong, Songzhi Li, Sidong Li, Chengpeng Yang, Lei  出版年:2018
Hemorrhea is one of the major problems in war, trauma care, and surgical operation that threaten the life of the injured and patients. As a novel polymeric hemostatic agent, biodegradable chitosan can stop bleeding throu...
Sponges of Carboxymethyl Chitosan Grafted with Collagen Peptides for Wound Healing
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESCheng, Yu Hu, Zhang Zhao, Yuntao Zou, Zuhao Lu, Sitong Zhang, Bijun Li, Sidong  出版年:2019
Burns are physically debilitating and potentially fatal injuries. Two marine biomaterials, carboxymethyl chitosan (CMC) and collagen peptides (COP), have emerged as promising burn dressings. In this paper, sponges of car...
Construction of a composite sponge containing tilapia peptides and chitosan with improved hemostatic performance
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESOuyang, Qianqian Hou, Tingting Li, Chengpeng Hu, Zhang Liang, Limei Li, Sidong Zhong, Qingkun Li, Puwang  出版年:2019
Despite superior hemostasis and repair function, tilapia peptide's application as wounding dressing is greatly limited due to its poor biostability. To expand its application in wounding dressing area, chitosan (CS), wit...
海藻酸钙多孔微球-白芨多糖复合止血粉的制备及止血性能评价
《高分子通报》王超 罗文峰 李普旺 李思东 杨子明 胡章 敖宁建  出版年:2017
海藻酸盐具有良好的生物相容性、可降解性、止血、抗菌、促愈合等特性,而中药白芨中的白芨多糖具有收敛止血、消肿生肌的功效。用海藻酸盐和白芨多糖为原料,采用冷冻干燥技术制备海藻酸钙多孔微球-白芨多糖复合止血粉,对其吸水速率进行...
关键词:海藻酸盐  微球  白芨多糖  止血  被引量:30
Marine collagen peptide grafted carboxymethyl chitosan: Optimization preparation and coagulation evaluation
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESCheng, Yu Lu, Sitong Hu, Zhang Zhang, Bijun Li, Sidong Hong, Pengzhi  出版年:2020
Uncontrolled bleeding has always been a sudden accident, which is the main cause of casualties in war trauma, emergency events and surgical operations. Rapid hemostatic materials can effectively reduce casualties and sav...
Chitosan-Based Thermo-Sensitive Hydrogel Loading Oyster Peptides for Hemostasis Application
MATERIALSZhang, Dongying Hu, Zhang Zhang, Lingyu Lu, Sitong Liang, Fengyan Li, Sidong  出版年:2020
Uncontrolled massive hemorrhage is one of the principal causes of death in trauma emergencies. By using catechol-modified chitosan (CS-C) as the matrix material and beta glycerol phosphate (beta-GP) as a thermo-sensitive...
Thermal degradation of agar: Mechanism and toxicity of products
FOOD CHEMISTRYOuyang, Qian-Qian Hu, Zhang Li, Si-Dong Quan, Wei-Yan Wen, Li-Li Yang, Zi-Ming Li, Pu-Wang  出版年:2018
The mechanism of the thermal degradation and the toxicity of the thermal degradation products of agar were studied using TG/DTA, Fourier-transform infrared spectroscopy and pyrolysis gas chromatography/mass spectrometry....
Preparation and Properties of Carboxymethyl Chitosan/Alginate/Tranexamic Acid Composite Films
MEMBRANESZhong, Qing-Kun Wu, Ze-Yin Qin, Ya-Qi Hu, Zhang Li, Si-Dong Yang, Zi-Ming Li, Pu-Wang  出版年:2019
In this study, the porous composite films of carboxymethyl chitosan/alginate/tranexamic acid were fabricated, with calcium chloride as the crosslinking agent and glycerin as a plasticizer. The composite films were charac...
Preparation and evaluation of squid ink polysaccharide-chitosan as a wound-healing sponge
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONSHuang, Na Lin, Jiali Li, Sidong Deng, Yifeng Kong, Songzhi Hong, Pengzhi Yang, Ping Liao, Mingneng Hu, Zhang  出版年:2018
A new type of wound healing agent was developed using two marine biomaterials (squid ink polysaccharide and chitosan) as carriers and calcium chloride as an initiator for coagulation. Based on central composite design re...
Gastric acid-response chitosan/alginate/tilapia collagen peptide composite hydrogel: Protection effects on alcohol-induced gastric mucosal injury
CARBOHYDRATE POLYMERSLu, Sitong Kong, Songzhi Wang, Ye Hu, Zhang Zhang, Lingyu Liao, Mingneng  出版年:2022
Long-term excessive alcohol intake can easily lead to gastritis, gastric ulcer, and gastric bleeding. In this paper, the gastric acid-responsive hydrogel of CS-NAC/alginate/tilapia collagen peptide (CS-NAC/ALG/TCP) was d...
Research Progress of Chitosan-Based Biomimetic Materials
MARINE DRUGSZhang, Zhaoyu Zhang, Lingyu Li, Chengpeng Xie, Xiangyu Li, Guangfa Hu, Zhang Li, Sidong  出版年:2021
Chitosan is a linear polysaccharide produced by deacetylation of natural biopolymer chitin. Owing to its good biocompatibility and biodegradability, non-toxicity, and easy processing, it has been widely used in many fiel...
基于自主学习能力培养的有机化学课程教学改革探索
《高教论坛》胡章  出版年:2019
有机化学是地方高校农、林、牧、医、食品、水产和生物等相关专业的一门基础理论课,对于科学的认知和专业课的学习有着重要意义。以有机化学课程传统教学过程中自主学习能力培养不足等问题为导向开展研究,通过课程知识结构更新、教学方法...
关键词:有机化学课程  教学改革  创新实践  自主学习能力  被引量:7
Preparation and characterization of amphiphilic chitosan/iodine composite film as antimicrobial material
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESZhang, Lingyu Zhang, Zhaoyu Li, Chengpeng Hu, Zhang Liang, Youling Yang, Ziming Cheng, Yu Huang, Dejian  出版年:2022
The composite film of amphiphilic chitosan/iodine, poly(aminoethyl) chitosan citronellal Schiff base iodine (PACSC-I), was prepared, and characterized by SEM, AFM, FTIR, 1H NMR and XRD. The physicochemical properties of ...
壳聚糖基复合水凝胶在创伤修复中的应用
《应用化工》张冬英 卢思彤 胡章 李思东 李普旺  出版年:2019
综述了近年来壳聚糖与温敏材料、生长因子、多肽及多种其他材料通过物理或化学方法复合制备的壳聚糖基水凝胶及其在创伤修复领域中研究和应用的新进展,并对其发展前景进行了展望,期望为后续壳聚糖基水凝胶的进一步研究提供参考。
关键词:壳聚糖  水凝胶  创伤修复  被引量:6
制药工程专业实验课程教学改革实践与探索
《山东化工》廖铭能 胡章 黄娜 苗艳丽 李思东  出版年:2019
以广东海洋大学化学与环境学院制药工程专业为例,总结了该专业实验课程教学体系中存在的问题,并提出了相应的改革方案。依据该改革方案,本专业近五年本科毕业生的改革实践已取得显著成果,达到了对实验课程改革的初步目标。
关键词:制药工程  实验课程  教学改革  被引量:5
Preparation and characterization of catechol-functionalized chitosan thermosensitive hydrogels
2ND INTERNATIONAL CONFERENCE ON MATERIAL STRENGTH AND APPLIED MECHANICSZhang, D. Y. Hu, Z. Lu, S. T. Li, S. D. Yang, Z. M. Li, P. W.  出版年:2019
Catechol functionalization of chitosan was modified by EDC coupling reaction and then catechol-functionalized chitosan thermosensitive hydrogels were prepared by catechol-functionalization of chitosan with beta-glyceroph...
Optimization of preparation process and characterization of carboxymethyl chitosan/sodium alginate hemostatic sponge
2017 GLOBAL CONFERENCE ON POLYMER AND COMPOSITE MATERIALS (PCM 2017)Hu, Z. Ouyang, Q. Q. Cheng, Y. Hong, P. Z. Liao, M. N. Chen, F. J. Li, S. D.  出版年:2017
Composite hemostatic sponge was prepared by vacuum freeze-drying using carboxymethyl chitosan and sodium alginate as the main materials and CaCl2 as a crosslinking agent. On the basis of single factor experiments, an ort...
Preparation of Poly (Allylthiourea-Co-Acrylic Acid) Derived Carbon Materials and Their Applications in Wastewater Treatment
MOLECULESLiang, Limei Li, Chengpeng Hou, Tingting Zhong, Zhiying Chen, Dongchu Li, Sidong Hu, Zhang Yang, Haihua Ye, Xiufang  出版年:2019
Functional carbon materials have been developed and applied in various sewage treatment applications in recent years. This article reports the fabrication, characterization, and application of a new kind of poly (allylth...
Preparation of norfloxacin-grafted chitosan antimicrobial sponge and its application in wound repair
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESCheng, Yu Wang, Jiyuan Hu, Zhang Zhong, Saiyi Huang, Na Zhao, Yuntao Tao, Yi Liang, Youling  出版年:2022
Trauma is one of the most common health issues in humans, and bacterial infection of the wound may result in many complications. In this paper, using 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC) as a...
罗非鱼皮胶原蛋白肽在润肤霜中的应用及性能评价
《食品工业科技》李继城 孔松芝 李东东 李思东 胡章 郭敏慧  出版年:2018
本研究采用酶解法从罗非鱼皮中提取胶原蛋白肽,并对其基本成分、分子量分布、抗氧化活性、保湿性以及紫外吸收性能进行考察和分析,同时将提取到的罗非鱼皮肽与羧甲基壳聚糖按不同比例进行复配,应用到润肤霜中并进行性能评价。结果表明:...
关键词:罗非鱼皮  胶原蛋白肽  润肤霜  保湿性  抗氧化性  防晒  光老化  被引量:4
大学有机化学课程教学在创新创业背景下的实践思考
《轻工科技》胡章  出版年:2021
高等教育的目的是培养学生综合素质。在创新创业教育背景下高等教育既要重视培养学生创新思维和自主学习能力,又要培养学生扎实的专业基础、专业技能和专业综合应用与创新能力。有机化学是理科、工科类院校诸多专业的一门基础理论课,对于...
关键词:有机化学  创新创业  创新能力  教学改革  被引量:4
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