Mussel adhesive proteins (MAPs) have a unique ability to firmly adhere to different surfaces in aqueous environments via the special amino acid, 3,4-dihydroxyphenylalanine (DOPA). The catechol groups in DOPA are a key gr...
Fucoidan-a marine natural active polysaccharide derived from brown algae with a variety of medicinal activities and low toxicity-has been used as clinical drug for renal diseases for nearly 20 years. The pharmacological ...
Carboxymethylation modification is commonly used for improving physicochemical and biological properties of nature polysaccharides, effect of carboxymethylation on property of fucoidan from Laminaria japonica (FL) is sti...
This work aims to explore the amelioration of fucoidan on adenine-induced hyperuricemia and hepatorental damage. Adenine-induced hyperuricemic mice were administered with fucoidan, allopurinol and vehicle control respect...
In our recent reports, a squid ink polysaccharide (SIP) was found having preventive activity against cyclophosphamide induced damage in mouse testis and ovary. Here we further reveal the regulative mechanism of SIP again...
To investigate the effect of carboxymethylation and phosphorylation modification on Sepia esculenta ink polysaccharide (SIP) properties, this study prepared carboxymethyl SIP (CSIP) with the chloracetic acid method, and ...
This work aimed to investigate the effect of fucoidan (FPS) on urate transporters induced by uric acid (UA). The results showed that UA stimulated the expression of glucose transporter 9 (GLUT9) and urate transporter 1 (...
Sepia ink polysaccharide (SIP) isolated from squid and cuttlefish ink is a kind of acid mucopolysaccharide that has been identified in three types of primary structures from squid (Illex argentinus and Ommastrephes bartr...
The aim of this study was to determine the mechanisms driving the protective effects of squid ink polysaccharide (SIP) against cyclophosphamide (CP)-induced testicular damage, focusing on germ cells. In the testes of mic...
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTSLi, Yanqun Wang, Caijuan Liu, Huazhong Su, Junbiao Lan, Christopher Q. Zhong, Min Hu, Xueqiong 出版年：2020
Previous research revealed that green microalga Neochloris oleoabundans was able to excrete extracellular polysaccharides (EPS) in the media containing certain sugar, but detail researches on the production conditions an...
JOURNAL OF FOOD PROCESSING AND PRESERVATIONLuo, Ping Li, Fangping Liu, Huazhong Yang, Xiaomei Duan, Zhenhua 出版年：2020
To further investigate fresh-keeping effect of fucoidan from Laminaria japonica (FL) on postharvest strawberry, this study assessed the degradation kinetics of antioxidant capacity and antioxidants in cold-stored strawbe...
Oxidation injury to skin is one of the main reasons for skin aging. The aim of the present study was to explore the protective effect of squid ink polysaccharides and its mechanism of action against H2O2-induced dermal f...
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESLiu, Huazhong Zhang, Yunbo Li, Mingwei Luo, Ping 出版年：2019
In order to investigate prevention of squid ink polysaccharide (SIP) against cyclophosphamide (CP) induced ovarian failure and immunosuppression in mice, female Kunming mice were subjected to intraperitoneal injection of...
Objective(s): The aim of this study was to explore the effects of Squid ink polysaccharide (SIP) on prevention of autophagy and oxidative stress induced by cyclophosphamide (CP) in Leydig cells of mice. Materials and Met...
Chitosan is the only cationic polysaccharide found in nature. It has broad application prospects in biomaterials, but its application is limited due to its poor solubility in water. A novel chitosan derivative was synthe...
Saccharomyces cerevisiaewas used as a model to explore the preventive effect of two marine polysaccharides separately derived fromSepia esculentaink (SIP) andLaminaria japonica(FL) as well as one terrestrial polysacchari...
Carboxymethylated, phosphorylated and sulfated derivatives of SIP-IV, a polysaccharide derived from Sepia esculenta ink, were prepared and their antioxidant, anticoagulant and thrombolytic properties were evaluated. Data...
IRANIAN JOURNAL OF BASIC MEDICAL SCIENCESLiu, Hua-Zhong Xiao, Wei Gu, Yi-Peng Tao, Ye-Xing Zhang, Da-Yan Du, Hui Shang, Jiang-Hua 出版年：2016
Objective(s): This paper aims to investigate synergistic inhibition of polysaccharide from Sepia esculenta ink (SIP), a newly isolated marine polysaccharide in our laboratory, on breast cancer MDA-MB- 231 cells exposed t...
Although the toxicity of acrylamide (ACR) has been extensively investigated in different experimental models, its perturbations to multiple nodes of the cellular signaling network have not been systematically associated....
SCIENTIFIC REPORTSTan, Xiao-Hui Li, Yu-Bin Liao, Yan Liu, Hua-Zhong 出版年：2020
In this work, an enzyme-free fluorescence resonance energy transfer (FRET) strategy was established for rapid and specific detection of the DNA sequence from Vibrio parahaemolyticus (VP) using hybridization chain reactio...
Four fractions of water-extracted Sepia esculenta ink polysaccharides (SIP) were separated by dicthylaminoethy (DEAE) cellulose chromatography. The eluted fraction with the highest yield was characterized as a sulfate-ri...
SCIENCE OF THE TOTAL ENVIRONMENTLin, Zhen Wan, Gen Wu, Jiayi Liu, Huazhong Zhang, Fan Tang, Xiaochen Ruan, Jiming 出版年：2023
To further explore short-term exposure of enrofloxacin (ENR) induced toxicity in crucian carp brain that has been reported by our previous work, as well as the possible toxicological mechanisms, this study investigated t...
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESWu, Jiayi Zheng, Wenyan Luo, Ping Lin, Zhen Li, Fangping Liang, Linlin Liu, Huazhong 出版年：2024
Four main water-soluble wampee fruit pulp polysaccharides, named CSP-I, CSP-II, CSP-III and CSP-IV, were isolated from Clausena lansium (Lour.) Skeels Guifei, therein CSP-IV content was higher than the others. All compon...
In order to further explore the potential pharmacological activity of astaxanthin (AST), network pharmacological approaches were employed in this work to systematically investigate its affinity targets, perturbed signali...
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRYYuan, Jiaming Wu, Yulian Kang, Xinhuang Liu, Huazhong Li, Yubin 出版年：2020
Detection of divalent mercury attracts great significance in most biological and environmental systems. In this study, a Thymine-divalent mercuric ions-Thymine (T-Hg2+-T) structure based colorimetric assay with Exonuclea...
DRUG AND CHEMICAL TOXICOLOGYLin, Zhen Liu, Huazhong Yang, Chunyan Zheng, Haiying Zhang, Yu Su, Weiming Shang, Jianghua 出版年：2022
Curcumin (Cur) is a flavonoid derived from Curcuma longa L. that has been shown to have a variety of biological activities, but some previous studies have described its non-negligible negative effects on female reproduct...
PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCESLuo, Ping Liu, Hua-Zhong Le, Xiao-Yan Du, Hui Kang, Xin-Huang 出版年：2018
The present study was conducted to investigate the preventive effects of squid ink polysaccharides (SIP) on the damage of sperm and reproduction induced by cyclophosphamide that is most commonly used for treating clinica...
Background: Preservative effect of melanin-free extract of Sepia esculenta ink (MFESI) on Sparus latus fillet has been verified in our previous work. This study aims to further approach the mechanism of MFESI for extendi...
Daucosterol, a natural saponin from Eleocharis dulcis peel, exhibited anti-hyperglycemic properties. This study investigated daucosterol's effects on glycemic control, insulin resistance, and gut microbiota in type 2 dia...
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