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被引量:1,905H指数:22SCI-EXPANDED: 34EI: 30北大核心: 15CSCD: 12

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82 条 记 录,以下是 1-30

Chitosan-Based Composite Materials for Prospective Hemostatic Applications
MARINE DRUGSHu, Zhang Zhang, Dong-Ying Lu, Si-Tong Li, Pu-Wang Li, Si-Dong  出版年:2018
Effective hemostasis is vital to reduce the pain and mortality of patients, and the research and development of hemostatic materials are prerequisite for effective hemostasis. Chitosan (CS), with good biodegradability, b...
Marine Collagen Peptides from the Skin of Nile Tilapia (<i>Oreochromis niloticus</i>): Characterization and Wound Healing Evaluation
MARINE DRUGSHu, Zhang Yang, Ping Zhou, Chunxia Li, Sidong Hong, Pengzhi  出版年:2017
Burns can cause tremendous economic problems associated with irreparable harm to patients and their families. To characterize marine collagen peptides (MCPs) from the skin of Nile tilapia (Oreochromis niloticus), molecul...
Preparation and evaluation of chitosan/alginate porous microspheres/<i>Bletilla striata</i> polysaccharide composite hemostatic sponges
CARBOHYDRATE POLYMERSWang, Chao Luo, Wenfeng Li, Puwang Li, Sidong Yang, Ziming Hu, Zhang Liu, Yangyang Ao, Ningjian  出版年:2017
We prepared a novel hemostatic material using chitosan (CS), alginate, and Bletilla striata, which showed good biocompatibility and hemostatic properties. Alginate-calcium porous microspheres (Alg) were prepared by emuls...
A sodium alginate-based sustained-release IPN hydrogel and its applications
RSC ADVANCESZou, Zuhao Zhang, Bijun Nie, Xiaoqin Cheng, Yu Hu, Zhang Liao, Mingneng Li, Sidong  出版年:2020
Interpenetrating polymer network (IPN) hydrogels are crosslinked by two or more polymer networks, providing free volume space in the three-dimensional network structure, and providing conditions for the sustained and con...
Catechol functionalized chitosan/active peptide microsphere hydrogel for skin wound healing
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESZhang, Dongying Ouyang, Qianqian Hu, Zhang Lu, Sitong Quan, Weiyan Li, Puwang Chen, Yu Li, Sidong  出版年:2021
Chitosan-based thermosensitive hydrogels have been widely used in drug delivery and tissue engineering, but their poor bioactivity has limited their further applications. Integral active oyster peptide microspheres (OPM)...
Mussel-Inspired Catechol-Functionalized Hydrogels and Their Medical Applications
MOLECULESQuan, Wei-Yan Hu, Zhang Liu, Hua-Zhong Ouyang, Qian-Qian Zhang, Dong-Ying Li, Si-Dong Li, Pu-Wang Yang, Zi-Ming  出版年:2019
Mussel adhesive proteins (MAPs) have a unique ability to firmly adhere to different surfaces in aqueous environments via the special amino acid, 3,4-dihydroxyphenylalanine (DOPA). The catechol groups in DOPA are a key gr...
Chitosan hydrogel in combination with marine peptides from tilapia for burns healing
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESOuyang, Qian-Qian Hu, Zhang Lin, Zhen-Peng Quan, Wei-Yan Deng, Yi-Feng Li, Si-Dong Li, Pu-Wang Chen, Yu  出版年:2018
The purpose of this study was to develop a promising burns dressing. Chiosan (CS) has been widely used as biomaterials, in combination with marine peptides (MPs) extracted from seawater cultured Tilapia, the newly develo...
Anti-Aging Effect of Chitosan Oligosaccharide on D-Galactose-Induced Subacute Aging in Mice
MARINE DRUGSKong, Song-Zhi Li, Ji-Cheng Li, Si-Dong Liao, Ming-Neng Li, Cheng-Peng Zheng, Pin-Jin Guo, Min-Hui Tan, Wei-Xiang Zheng, Zhao-Hui Hu, Zhang  出版年:2018
Chitosan oligosaccharide (COS), a natural polysaccharide with good antioxidant and anti-inflammatory properties, is the depolymerized product of chitosan possessing various biological activities. The present study was de...
Anti-photoaging effects of chitosan oligosaccharide in ultraviolet-irradiated hairless mouse skin
EXPERIMENTAL GERONTOLOGYKong, Song-Zhi Li, Dong-Dong Luo, Hui Li, Wen-Jie Huang, Yong-Mei Li, Ji-Cheng Hu, Zhang Huang, Na Guo, Min-Hui Chen, Yao Li, Si-Dong  出版年:2018
Skin photoaging (SP) is a premature skin-aging damage after repeated exposure to ultraviolet (UV) radiation, mainly characterized by oxidative stress and inflammatory disequilibrium, which makes skin show the typical sym...
Gastric acid-response chitosan/alginate/tilapia collagen peptide composite hydrogel: Protection effects on alcohol-induced gastric mucosal injury
CARBOHYDRATE POLYMERSLu, Sitong Kong, Songzhi Wang, Ye Hu, Zhang Zhang, Lingyu Liao, Mingneng  出版年:2022
Long-term excessive alcohol intake can easily lead to gastritis, gastric ulcer, and gastric bleeding. In this paper, the gastric acid-responsive hydrogel of CS-NAC/alginate/tilapia collagen peptide (CS-NAC/ALG/TCP) was d...
Preparation and evaluation of chitosan/alginate porous microspheres/Bletilla striata polysaccharide composite hemostatic sponges
Carbohydrate PolymersWang, Chao Luo, Wenfeng Li, Puwang Li, Sidong Yang, Ziming Hu, Zhang Liu, Yangyang Ao, Ningjian  出版年:2017
We prepared a novel hemostatic material using chitosan (CS), alginate, and Bletilla striata, which showed good biocompatibility and hemostatic properties. Alginate-calcium porous microspheres (Alg) were prepared by emuls...
Sponges of Carboxymethyl Chitosan Grafted with Collagen Peptides for Wound Healing
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESCheng, Yu Hu, Zhang Zhao, Yuntao Zou, Zuhao Lu, Sitong Zhang, Bijun Li, Sidong  出版年:2019
Burns are physically debilitating and potentially fatal injuries. Two marine biomaterials, carboxymethyl chitosan (CMC) and collagen peptides (COP), have emerged as promising burn dressings. In this paper, sponges of car...
Investigation of the Effects of Molecular Parameters on the Hemostatic Properties of Chitosan
MOLECULESHu, Zhang Lu, Sitong Cheng, Yu Kong, Songzhi Li, Sidong Li, Chengpeng Yang, Lei  出版年:2018
Hemorrhea is one of the major problems in war, trauma care, and surgical operation that threaten the life of the injured and patients. As a novel polymeric hemostatic agent, biodegradable chitosan can stop bleeding throu...
Chitosan-Based Thermo-Sensitive Hydrogel Loading Oyster Peptides for Hemostasis Application
MATERIALSZhang, Dongying Hu, Zhang Zhang, Lingyu Lu, Sitong Liang, Fengyan Li, Sidong  出版年:2020
Uncontrolled massive hemorrhage is one of the principal causes of death in trauma emergencies. By using catechol-modified chitosan (CS-C) as the matrix material and beta glycerol phosphate (beta-GP) as a thermo-sensitive...
Construction of a composite sponge containing tilapia peptides and chitosan with improved hemostatic performance
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESOuyang, Qianqian Hou, Tingting Li, Chengpeng Hu, Zhang Liang, Limei Li, Sidong Zhong, Qingkun Li, Puwang  出版年:2019
despite superior hemostasis and repair function, tilapia peptide's application as wounding dressing is greatly limited due to its poor biostability. To expand its application in wounding dressing area, chitosan (CS), wit...
Marine collagen peptide grafted carboxymethyl chitosan: Optimization preparation and coagulation evaluation
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESCheng, Yu Lu, Sitong Hu, Zhang Zhang, Bijun Li, Sidong Hong, Pengzhi  出版年:2020
Uncontrolled bleeding has always been a sudden accident, which is the main cause of casualties in war trauma, emergency events and surgical operations. Rapid hemostatic materials can effectively reduce casualties and sav...
Thermal degradation of agar: Mechanism and toxicity of products
FOOD CHEMISTRYOuyang, Qian-Qian Hu, Zhang Li, Si-Dong Quan, Wei-Yan Wen, Li-Li Yang, Zi-Ming Li, Pu-Wang  出版年:2018
The mechanism of the thermal degradation and the toxicity of the thermal degradation products of agar were studied using TG/DTA, Fourier-transform infrared spectroscopy and pyrolysis gas chromatography/mass spectrometry....
海藻酸钙多孔微球-白芨多糖复合止血粉的制备及止血性能评价
《高分子通报》王超 罗文峰 李普旺 李思东 杨子明 胡章 敖宁建  出版年:2017
海藻酸盐具有良好的生物相容性、可降解性、止血、抗菌、促愈合等特性,而中药白芨中的白芨多糖具有收敛止血、消肿生肌的功效。用海藻酸盐和白芨多糖为原料,采用冷冻干燥技术制备海藻酸钙多孔微球-白芨多糖复合止血粉,对其吸水速率进行...
关键词:海藻酸盐  微球  白芨多糖  止血  被引量:33
Preparation and evaluation of squid ink polysaccharide-chitosan as a wound-healing sponge
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONSHuang, Na Lin, Jiali Li, Sidong Deng, Yifeng Kong, Songzhi Hong, Pengzhi Yang, Ping Liao, Mingneng Hu, Zhang  出版年:2018
A new type of wound healing agent was developed using two marine biomaterials (squid ink polysaccharide and chitosan) as carriers and calcium chloride as an initiator for coagulation. Based on central composite design re...
Preparation and Properties of Carboxymethyl Chitosan/Alginate/Tranexamic Acid Composite Films
MEMBRANESZhong, Qing-Kun Wu, Ze-Yin Qin, Ya-Qi Hu, Zhang Li, Si-Dong Yang, Zi-Ming Li, Pu-Wang  出版年:2019
In this study, the porous composite films of carboxymethyl chitosan/alginate/tranexamic acid were fabricated, with calcium chloride as the crosslinking agent and glycerin as a plasticizer. The composite films were charac...
Research Progress of Chitosan-Based Biomimetic Materials
MARINE DRUGSZhang, Zhaoyu Zhang, Lingyu Li, Chengpeng Xie, Xiangyu Li, Guangfa Hu, Zhang Li, Sidong  出版年:2021
Chitosan is a linear polysaccharide produced by deacetylation of natural biopolymer chitin. Owing to its good biocompatibility and biodegradability, non-toxicity, and easy processing, it has been widely used in many fiel...
Photothermal Ti<sub>2</sub>O<sub>3</sub>/polyurethane/polyacrylamide foam with high solar-evaporation efficiency
DESALINATIONLi, Lefan Zhao, Pengfei Wang, Zhifen Hu, Zhang Wang, Di Zhang, Yucang Li, Sidong Li, Chengpeng  出版年:2023
Photothermal material is indispensable for the fabrication of solar steam generation with easy-manufacture, cost-effective, and high-performance. Here, Ti2O3/polyacrylamide/polyurethane foams (Ti2O3/PU/PAM) were rational...
Preparation and characterization of 6-O-caffeic acid chitosan
Journal of Physics: Conference SeriesChen, W.P. Huang, D.J. Hu, Z. Zhuang, Y.L. Lu, S.T.  出版年:2021
The modified chitosan retains the excellent properties of chitosan and can broaden its application. In this paper, an approach of protection-deprotection was used to synthesize 6-O-caffeic acid chitosan with chitosan as ...
Preparation of norfloxacin-grafted chitosan antimicrobial sponge and its application in wound repair
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESCheng, Yu Wang, Jiyuan Hu, Zhang Zhong, Saiyi Huang, Na Zhao, Yuntao Tao, Yi Liang, Youling  出版年:2022
Trauma is one of the most common health issues in humans, and bacterial infection of the wound may result in many complications. In this paper, using 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC) as a...
Preparation and characterization of amphiphilic chitosan/iodine composite film as antimicrobial material
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESZhang, Lingyu Zhang, Zhaoyu Li, Chengpeng Hu, Zhang Liang, Youling Yang, Ziming Cheng, Yu Huang, Dejian  出版年:2022
The composite film of amphiphilic chitosan/iodine, poly(aminoethyl) chitosan citronellal Schiff base iodine (PACSC-I), was prepared, and characterized by SEM, AFM, FTIR, 1H NMR and XRD. The physicochemical properties of ...
Preparation, characterization and hemostatic properties of chitosan caffeates
Key Engineering MaterialsLu, Sitong Zhang, Dongying Hu, Zhang Li, Sidong Li, Puwang  出版年:2019
In this paper, chitosan and caffeic acid were used as starting materials to prepare chitosan caffeates by reflux-heating and freeze-drying. The structures of chitosan caffeates were characterized by Fourier transform inf...
Fabrication and Characterization of Marine Polysaccharides Hemostatic Dressing
IOP Conference Series: Materials Science and EngineeringZhong, Qing-Kun Hu, Zhang Zhang, Dong-Ying Li, Si-Dong  出版年:2018
Marine polysaccharides composite hemostatic dressing was fabricated with calcium chloride as the crosslinking agent and carboxymethyl chitosan/sodium alginate as raw materials. On the basis of the pre-experiment, the fab...
Preparation and characterization of catechol-functionalized chitosan thermosensitive hydrogels
IOP Conference Series: Materials Science and EngineeringZhang, D.Y. Hu, Z. Lu, S.T. Li, S.D. Yang, Z.M. Li, P.W.  出版年:2019
Catechol functionalization of chitosan was modified by EDC coupling reaction and then catechol-functionalized chitosan thermosensitive hydrogels were prepared by catechol-functionalization of chitosan with β-glycerophosp...
Optimization of preparation process and characterization of carboxymethyl chitosan/sodium alginate hemostatic sponge
2017 GLOBAL CONFERENCE ON POLYMER AND COMPOSITE MATERIALS (PCM 2017)Hu, Z. Ouyang, Q. Q. Cheng, Y. Hong, P. Z. Liao, M. N. Chen, F. J. Li, S. D.  出版年:2017
Composite hemostatic sponge was prepared by vacuum freeze-drying using carboxymethyl chitosan and sodium alginate as the main materials and CaCl2 as a crosslinking agent. On the basis of single factor experiments, an ort...
季铵化改性壳聚糖的制备及其凝血性能研究
《应用化工》梁倩瑜 翁博雅 黄美茹 陈丽红 贺怡心 胡章  出版年:2023
为了对壳聚糖进行化学改性及探究其凝血性能,以来源丰富的壳聚糖为起始原料,通过亲核取代反应,开展季铵化改性,采用紫外-可见光谱、红外光谱及X-射线衍射进行结构表征,并在体外探索其凝血性能。化学结构表征结果表明,季铵化壳聚糖...
关键词:壳聚糖  季铵化改性  凝血  被引量:10
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