The gut-associated lymphoid tissue, connected with liver via bile and blood, constructs a local immune environment of both defense and tolerance. The gut-liver immunity has been well-studied in mammals, yet in fish remai...
JOURNAL OF BACTERIOLOGYWang, Bei Jian, Jichang Lu, Yishan Cai, Shuanghu Huang, Yuchong Tang, Jufen Wu, Zaohe 出版年：2012
Streptococcus agalactiae (group B streptococcus [GBS]) is a pathogen that causes meningoencephalitis in Nile tilapia (Oreochromis niloticus). Here, we reported the complete genome sequence of S. agalactiae strain ZQ0910,...
MicroRNAs are a kind of small non-coding RNAs that participate in various biological processes. Deregulated microRNA expression is associated with several types of diseases. Tilapia (Oreochromis niloticus) is an importan...
REVIEWS IN AQUACULTUREWang, Bei Thompson, Kim D. Wangkahart, Eakapol Yamkasem, Jidapa Bondad-Reantaso, Melba G. Tattiyapong, Puntanat Jian, Jianchang Surachetpong, Win 出版年：2023
Various emerging and re-emerging diseases, such as streptococcosis, tilapia lake virus disease and infectious spleen and kidney necrosis virus disease, have had a significant economic impact on the tilapia industry over ...
FISH & SHELLFISH IMMUNOLOGYWangkahart, Eakapol Wachiraamonloed, Suriyet Lee, Po-Tsang Subramani, Parasuraman Aiya Qi, Zhitao Wang, Bei 出版年：2022
An experiment was conducted to investigate the effects of Aegle marmelos fruit (AMF) extract on the growth performance, biochemical parameters, immune response, antioxidative capacity, and digestive enzyme activity of Ni...
FISH & SHELLFISH IMMUNOLOGYWangkaghart, Eakapol Deville, Sebastien Wang, Bei Srisapoome, Prapansak Wang, Tiehui Secombes, Christopher J. 出版年：2021
Streptococcus agalactiae is one of the most important pathogens infecting tilapia worldwide and causes meningoencephalitis, septicemia and high mortalities with considerable losses. Various types of vaccines have been de...
Non-specific cytotoxic cells (NCC) are important cytotoxic leukocytes in teleost immune system. However, the NCC subsets have not been clarified. Thus, we create a comprehensive cell map of similar to 24,062 head kidney-...
NK-lysin, an effector of cytotoxic T cells and natural killer cells, is a potent antimicrobial peptide widely distributed in mammals. Homologues of NK-lysin have been discovered in several teleost species, but only sever...
MOLECULAR BIOLOGY AND EVOLUTIONWang, Bei Wangkahart, Eakapol Secombes, Christopher J. Wang, Tiehui 出版年：2019
The SOCS family are key negative regulators of cytokine and growth factor signaling. Typically, 8-17 SOCS genes are present in vertebrate species with eight known in mammals, classified as type I (SOCS4-7) and type II (C...
CD2BP2 (CD2 cytoplasmic tail binding protein 2), one of several proteins interacting with the cytoplasmic tail of CD2, plays a crucial role in CD2-triggered T cell activation and nuclear splicing. The studies on CD2BP2 h...
GENEWang, Zhongliang Wang, Bei Chen, Gang Jian, Jichang Lu, Yishan Xu, Youhou Wu, Zaohe 出版年：2016
The pearl oyster Pinctada fucata is cultured widely for production of marine pearls in China, while mass mortalities, likely related to pathogenic infections, have occurred frequently in juvenile, mother and operated oys...
Galectin-8 is a member of the galectin family that is involved in immune response against pathogens. However, the roles of fish galectin-8 during pathogen infection require comprehensive studies. In this study, a galecti...
FRONTIERS IN IMMUNOLOGYLiao, Xuzheng Wang, Chenggui Wang, Bo Qin, Haipeng Hu, Shikang Wang, Ping Sun, Chengbo Zhang, Shuang 出版年：2020
Decapod iridescent virus 1 (DIV1) results in severe economic losses in shrimp aquaculture. However, little is known about the physiological effect of DIV1 infection on the host. In this study, we found that the lethal do...
In the present study, members of the interleukin (IL)-10 family of cytokines, including IL-10 (TOIL-10) and IL-22 (TOIL-22) of golden pompano (Trachinotus ovatus), were cloned for the first time, and their expression pat...
FISH & SHELLFISH IMMUNOLOGYGan, Zhen Wang, Bei Zhou, Wei Lu, Yishan Zhu, Weiwei Tang, Jufen Jan, JiChang Wu, Zaohe 出版年：2015
CD59, the major inhibitor of membrane attack complex, plays a crucial role in regulation of complement activation. In this paper, a CD59 gene of Nile tilapia, Oreochromis niloticus (designated as On-CD59) was cloned and ...
DISEASES OF AQUATIC ORGANISMSCai, X. H. Peng, Y. H. Wang, Z. C. Huang, T. Xiong, X. Y. Huang, Y. C. Wang, B. Xu, L. W. Wu, Z. H. 出版年：2016
Streptococcal infections cause significant mortality and high economic losses in the fish farm industry worldwide, including in the culture of golden pompano Trachinotus ovatus L., a species gaining popularity in China. ...
LETTERS IN APPLIED MICROBIOLOGYCai, S. H. Lu, Y. S. Wu, Z. -H. Jian, J. C. Wang, B. Huang, Y. C. 出版年：2010
Aims: The purpose of this study was to develop a loop-mediated isothermal amplification (LAMP) method for the rapid, sensitive and simple detection of Vibrio alginolyticus in mariculture fish. Methods and Results: LAMP p...
The cDNA of a tandem-repeat galectin from the pearl oyster Pinctada fucata (designated PfGal) was cloned by expressed sequence tag (EST) and rapid amplification of cDNA ends (RACE) techniques. The full-length cDNA of PfG...
The pathogenesis of tilapia meningoencephalitis is still unclear, where the involvement of circRNA is considered for its active role as a `` miRNA sponge''. Therefore, we aimed to investigate the profile of circRNA in ti...
Antibacterial peptides (AMPS) are expected to replace some or all of the antibiotics and become a new feed additive. However, the high production cost and unclear mechanism limited the application of AMPS. In this resear...
The banana shrimp (Fenneropenaeus merguiensis) is a common cultural species worldwide. With the development of the shrimp farming industry, increasing number of diseases have emerged and cause huge impacts. Decapod iride...
Galectin-9 is a < beta > -galactoside-binding lectin which could modulate a variety of biological functions including recognition, aggregation and clearance of pathogen. In this study, a galectin-9 homologue (OnGal-9) wa...
Nocardia seriolae is a pathogen that causes nocardiosis in marine and freshwater fish. Here, we report the draft genome sequence of N. seriolae strain ZJ0503, which was isolated from Trachinotus ovatus in Guangdong, Chin...
FISH & SHELLFISH IMMUNOLOGYWang, Bei Gan, Zhen Wang, Zhongliang Yu, Dapeng Lin, Ziwei Lu, Yishan Wu, Zaohe Jian, Jichang 出版年：2017
MicroRNAs (miRNAs) are a class of noncoding RNA molecules and play important roles in a wide spectrum of biological processes, including in immune response. Recent years have witnessed considerable amount of research int...
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESWang, Bei Wang, Pei Wu, Zao-He Lu, Yi-Shan Wang, Zhong-Liang Jian, Ji-Chang 出版年：2016
IgD is considered to be a recently-evolved Ig and a puzzling molecule, being previously found in all vertebrate taxa, except for birds. Although IgD likely plays an important role in vertebrate immune responses, the func...
DISEASES OF AQUATIC ORGANISMSCai, Shuang-Hu Yao, Shao-Yun Lu, Yi-Shan Wu, Zao-He Jian, Ji-Chang Wang, Bei 出版年：2010
The outer membrane proteins (OMPs) of the marine aquatic animal pathogen Vibrio alginolyticus play an important role in the virulence of the bacterium and are potential candidates for vaccine development. In this study, ...
DISEASES OF AQUATIC ORGANISMSCai, Shuang-Hu Lu, Yi-Shan Jian, Ji-Chang Wang, Bei Huang, Yu-Cong Tang, Ju-Fen Ding, Yu Wu, Zao-He 出版年：2013
The outer membrane proteins of Vibrio alginolyticus play an important role in the virulence of the bacterium and are potential candidates for vaccine development. In the present study, the ompW gene was cloned, expressed...
Galectin-3 is a kind of beta-galactoside-binding lectin involved in host defense against pathogen infection. However, the immune functions of fish galectin-3 remain poorly understood. In this study, the roles of a fish g...
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